Protein Alignment CG46301 and NOL4L

DIOPT Version :9

• Sequence 1: NP_001334737.1
• Gene: CG46301 / 34829
• FlyBaseID: FBgn0283651
• Length: 1237
• Species: Drosophila melanogaster
• Sequence 2: NP_001243727.1
• Gene: NOL4L / 140688
• HGNCID: 16106
• Length: 680
• Species: Homo sapiens
• Alignment Length: 1197
• Identity: 299/1197 - (24%)
• Similarity: 407/1197 - (34%)
• Gaps: 557/1197 - (46%)

  Fly    67 ELEQPTAEREIIYELFQPWALSTYGDQAKTKTITLRKKARILKALEG----KEHSRP---DSSKF 124
            |.|:...:.|:..: |:.|.|.||||.|||||:|..|..||.:.|:|    ...|.|   :..||
Human    13 ERERSPGDSELGRQ-FRDWCLRTYGDSAKTKTVTRSKYQRIAEVLQGGGGTGAGSGPAAGEKGKF 76

  Fly   125 RFWVKTKGFTTNRPEGFEEAPGSRRHLK--NLPSSAILSDNPADVDLFAASTSKGFGRRTYRKVA 187
            :|||::|||..          ||.|..|  .:....:.:.:.||    ..|..:|.   :.::||
Human    77 QFWVRSKGFRL----------GSGREPKMGQVVYVPVKTGSGAD----GLSEPEGI---SLKRVA 124

  Fly   188 CVEEFFDIIYNVHMELG---GRSGMHAGQKRTYRIITETYAFLPREAVTRFLTICPECKKNLRPS 249
            .||:||||||::|:|..   |::..|||||:|||.|.|||||||||||||||..|.||:|.:..:
Human   125 VVEDFFDIIYSMHVESSAEPGKAPKHAGQKKTYRAIAETYAFLPREAVTRFLMSCTECQKRMHFN 189

  Fly   250 SPSGGGKDSDLAGNESSSE-VENYLNYSSHTESSLEAGPTAKRRRHSSAEIKASLASGLAVGAGV 313
            |.....|:     ||..|. |...::|:
Human   190 SNGLEPKE-----NEPPSPLVSGIIDYN------------------------------------- 212

  Fly   314 ASSMSATQLDVLWTGVPRSRSPKPPMAAEAAVETTPVSVPKIRIKTQLQRPSSPQDQSPADPNTD 378
             ..:::|.|..:...|..|:..          :.|.||.....:.......:.|...|...|:.|
Human   213 -MPLTSTYLKQMKLRVMNSQEQ----------DETSVSSEDFDMSDSTWMSADPHLASSLSPSQD 266

  Fly   379 AQSQSQIQSQSQSQSQSQSQSHSQPSGQGFDAQLLKSRDNLLRYYNFMRRFYAGEPVLAPPIYGS 443
            .:.:|.....||....|.|:|   .||.|
Human   267 ERMRSPQNLHSQEDDDSSSES---GSGNG------------------------------------ 292

  Fly   444 SLLQSLSYPTTISTAATATPTTPTTTTSAPGKMLAPPKTATPPPNPPKIKTSPDSLLRARTPPVA 508
                          ::|..|:|.::|...|         |.|..|
Human   293 --------------SSTLNPSTSSSTQGDP---------AFPEMN-------------------- 314

  Fly   509 STATSAAPKDAAHTPINLTKSLFSSLKTGHAPSTSTPVPLKLELPSPPKPLPELRIPQLRGMPPV 573
                    .:.|..|::.|.:           :...|:.|..:||
Human   315 --------GNGAVAPMDFTTA-----------AEDQPINLCDKLP-------------------- 340

  Fly   574 ELSLPLPPLDLERLKPITSTYLQLTRSMGLSDEDALRFDNLETIPATPVVSTDTASVVGVGVGGG 638
                                                        |||.:
Human   341 --------------------------------------------PATAL---------------- 345

  Fly   639 GGAAAGAGGGAGGAGGLLGDVVSGLGGGLVNESEAYAGLMKDADKLKLMLLAWNYQNSTAVRNGT 703
             |.|:....|. ||.||...|..|                                    |:...
Human   346 -GTASYPSDGC-GADGLRSRVKYG------------------------------------VKTTP 372

  Fly   704 EGPDLSVVGGLWAQYQNALAQNAAAAAAASGKMDS---SLSPVPRQDAHSPMETQDETNSSGQKE 765
            |.|..|                       ||..||   .:|..|.........|.|:       :
Human   373 ESPPYS-----------------------SGSYDSIKTEVSGCPEDLTVGRAPTADD-------D 407

  Fly   766 EDEVSEDDSDDKLDEKLATTHDPERLKAFNMFVRLFVDENLDRIIPISKQPKEKIQAIIDSCARQ 830
            :|:..:.:.:||:::  :...||||||||||||||||||||||::||||||||||||||:||:||
Human   408 DDDHDDHEDNDKMND--SEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQ 470

  Fly   831 FPEFSDRSRKRIRTYLKSCRRNKKTRDGWENTTRPTPAHLTSVQAEQILAIACENESMN-AKRMR 894
            ||||.:|:|||||||||||||.||  :|.| .|||||.||||..||.|||.|||:|:.. |||||
Human   471 FPEFQERARKRIRTYLKSCRRMKK--NGME-MTRPTPPHLTSAMAENILAAACESETRKAAKRMR 532

  Fly   895 IGLEPITHAVPAPGSAVAAAAAAAAAAAVVAATSSSAGGTSTTAAGNATATCGMGGVGDATGLTS 959
            :.:
Human   533 LEI-------------------------------------------------------------- 535

  Fly   960 AAAAALPFVSAVGFARSTPNSEHADVLPFGGAGTAGGSGGGGAGGGGGGGMSSARSSPLALSSNA 1024
                                                              ..|::..|:||....
Human   536 --------------------------------------------------YQSSQDEPIALDKQH 550

  Fly  1025 SVSGGASVTGLTLANGAGASNGAGLPASSPYTTDFSSPSTASPFVAAAAAVAAGRAPSYPGYF-- 1087
            | ...|::|..|.:          ||||| |:.|   |..|:          .|...||.||.
Human   551 S-RDSAAITHSTYS----------LPASS-YSQD---PVYAN----------GGLNYSYRGYGAL 590

  Fly  1088 ------PAVAGLGNVT--PTDLSMKPTSGLGGNMVSNNNSNSSVTGNINSQLSAANLASLSNASN 1144
                  ||....||.:  |||||||     ||         :|.|       |.....:.|:.|.
Human   591 SSNLQPPASLQTGNHSNGPTDLSMK-----GG---------ASTT-------STTPTPTPSSTST 634

  Fly  1145 NNALVTATQQLQQLQQQQQQQQQQQQQQQQQQLLVAGGGGMDGQSVRAPPILPHKLSANEVTAAR 1209
            :..:.||                                               :||..|::|.|
Human   635 SRPVPTA-----------------------------------------------QLSPTEISAVR 652

  Fly  1210 QVISAYRESAAFLLRTADQVEQLLVQQ 1236
            |:|:.||||||||||:||::|.|::||
Human   653 QLIAGYRESAAFLLRSADELENLILQQ 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46301	NP_001334737.1	None
NOL4L	NP_001243727.1	Integrase_H2C2	131..185	CDD:407771	34/53 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003616
OrthoInspector	1	1.000	-	-		otm41508
orthoMCL	1	0.900	-	-		OOG6_106349
Panther	1	1.100	-	-	O	PTHR12449
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2493
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.000