Protein Alignment CG46301 and LOC1277782

DIOPT Version :10

• Sequence 1: NP_001334737.1
• Gene: CG46301 / 34829
• FlyBaseID: FBgn0283651
• Length: 1237
• Species: Drosophila melanogaster
• Sequence 2: XP_061518486.1
• Gene: LOC1277782 / 1277782
• VectorBaseID: AGAMI1_009404
• Length: 999
• Species: Anopheles gambiae
• Alignment Length: 1169
• Identity: 402/1169 - (34%)
• Similarity: 539/1169 - (46%)
• Gaps: 399/1169 - (34%)

  Fly    75 REIIYELFQPWALSTYGDQAKTKTITLRKKARILKALEGKEHSRPDSSKFRFWVKTKGFTTNRPE 139
            |:.::|:||||.:.||||:||||||||:|:|||:|.|.|.|.:.|||||||||||||||||::|.
Mosquito   224 RDQMFEIFQPWVIRTYGDRAKTKTITLKKQARIIKTLRGLEMNNPDSSKFRFWVKTKGFTTSKPG 288

  Fly   140 GFEEAPGSRRHLKNLPSSAILSDNPADVDLFAASTSKGFGRRTYRKVACVEEFFDIIYNVHMELG 204
            .|::   ...| :|:|      :|...: |:|.|.....| :.|:|||.||.||||||.||:.||
Mosquito   289 DFQD---MFTH-QNIP------ENDGCM-LYAPSGGLEPG-QPYKKVAVVENFFDIIYGVHVSLG 341

  Fly   205 GRSGMHAGQKRTYRIITETYAFLPREAVTRFLTICPECKKNLRPSSPSGGGKDSDLAGNESSSEV 269
            .|:..|||||||||.||||||||||||||:||::|.:|.|                    .:::|
Mosquito   342 SRATRHAGQKRTYRTITETYAFLPREAVTKFLSLCSQCSK--------------------LTTKV 386

  Fly   270 ENYLNYSSHTESSLEAGPTAKRRRHSSAEIKASLASGLAVGAGVASSMSATQLDVLWTGVPRSRS 334
                 |.|.:|..:|                                             ||:..
Mosquito   387 -----YLSKSEPRME---------------------------------------------PRNDD 401

  Fly   335 PKPPMAAEAAVETTPVSVPKIRIKTQLQRPSSPQDQSPADPNTDAQSQSQIQSQSQSQSQSQSQS 399
            ..||                   ..::.|||.           ||..|.     |::..:|||.
Mosquito   402 TVPP-------------------SERIPRPSE-----------DAALQC-----SKTTDRSQSS- 430

  Fly   400 HSQPSGQGFDAQLLKSRDNLLRYYNFMRRFYAGEPVLAPPIYGSSLLQSLSYPTTISTAATATPT 464
                                ||||..::..|..         |.|        ..:.:....||.
Mosquito   431 --------------------LRYYELLKNLYEN---------GKS--------NRLRSGGAVTPA 458

  Fly   465 TPTTTTSAPGKMLAPPKTATPPPNPPKIKTSPDSLLRARTPPVASTATSAAPKDAAHTPINLTKS 529
            ..||.....||           |...:..:.|:|.:    ..|.|:..:||........:::|
Mosquito   459 QLTTDDVENGK-----------PQIVRAVSRPNSAV----SEVLSSDRAAAAAGGGGNELSVT-- 506

  Fly   530 LFSSLKTG---HAPSTSTPVPLKLELPSPPKPLPELRIPQLRGMPPVELSLPLPPLDLERLKPIT 591
            :.:|.:.|   |.|:.......:.|.....|        :.|                .|..||.
Mosquito   507 VCASERNGSREHLPAVGLNNNNRSEKGDDGK--------RRR----------------RRTVPIA 547

  Fly   592 STYLQLTRSMGLSDEDALRFDNLETIPATPVVSTDTASVVGVGVGGGGGAAAGAGGGAGGAGGLL 656
            :|||.:|||.||:|:|||..|::    :.|..|..|.:         .|:.|.
Mosquito   548 ATYLDVTRSFGLADDDALNVDSI----SMPFNSETTEN---------NGSTAN------------ 587

  Fly   657 GDVVSGLGGGLVNESEAYAGLMKDADKLKLMLLAWNYQNSTA--VRNGTEGPDLSVVGGLWAQYQ 719
                       ....:|||||:|||||.||||||||||||.|  .:||.|||||:.:..||.|||
Mosquito   588 -----------TPSEDAYAGLIKDADKFKLMLLAWNYQNSAAGKSQNGGEGPDLATMTNLWQQYQ 641

  Fly   720 NALAQNAAAAAAASGKMDSSLSPVPRQDAHSPME-TQDETNSSGQKEEDEVSEDDSDDKLDEKLA 783
            ||||.        :||...:..||..:.: ||:| .|||||||.||:||::|||||:|:|:   |
Mosquito   642 NALAM--------TGKTSFNQLPVSERQS-SPIEQQQDETNSSEQKDEDDLSEDDSEDRLE---A 694

  Fly   784 TTHDPERLKAFNMFVRLFVDENLDRIIPISKQPKEKIQAIIDSCARQFPEFSDRSRKRIRTYLKS 848
            |.:|||||||||||||||||||||||||||||||||||||||||.||||||::|:||||||||||
Mosquito   695 TVNDPERLKAFNMFVRLFVDENLDRIIPISKQPKEKIQAIIDSCTRQFPEFAERARKRIRTYLKS 759

  Fly   849 CRRNKKTRDGWENTTRPTPAHLTSVQAEQILAIACENESMNAKRMRIGLEPITHAVPAPGSAVAA 913
            ||||||||:|||||:|||||||||||||||||:||||||:||||||||||||:..|..|
Mosquito   760 CRRNKKTREGWENTSRPTPAHLTSVQAEQILAVACENESLNAKRMRIGLEPISQTVSQP------ 818

  Fly   914 AAAAAAAAAVVAATSSSAGGTSTTAAGNATATCGMGGVGDATGLTSAAAAALPFVSAVGFARSTP 978
                ||.:.:.:|.|.:|..|......|...        ::|.:::..:..:..|..:....|||
Mosquito   819 ----AAVSFMTSAESPTAVPTMYQTLANREQ--------ESTSVSTIKSEPMTSVPKISPVPSTP 871

  Fly   979 NSEHADVLPFGGAGTAGGSGGGGAGGGGGGGMSSARSSPLALSSNASVSGGASVTGLTLANGAGA 1043
            ..:                            |:..:   |.:.|                  |.|
Mosquito   872 TPD----------------------------MNQMK---LNIPS------------------ASA 887

  Fly  1044 SNGAGLPASSPYTTDFSSPSTASPFVAAAAAVAAGRAPSYPGYFPAVAGLGNVTPTDLSMKPTSG 1108
            |:...:|.:.|..::|...:|.          .:.|:..|..:..:|
Mosquito   888 SSTPTIPTTVPTISNFHDYNTG----------FSNRSQHYQNFMNSV------------------ 924

  Fly  1109 LGGNMVSNNNSNSSVTGNINSQLSAANLASLSNASNNNALVTATQQLQQLQQQQQQQQQQQQQQQ 1173
                   ||:|::|.....|:.:|||..|:.::.|...
Mosquito   925 -------NNSSSTSSGATTNTTMSAAGTAAPTDLSMKR--------------------------- 955

  Fly  1174 QQQLLVAGGGGMDGQSVRAPPILPHKLSANEVTAARQVISAYRESAAFLLRTADQVEQLLVQQQ 1237
                                |||.|||::.|:||.:|:::.||||||||:|:||::|.||:|||
Mosquito   956 --------------------PILAHKLNSAEITAVKQLVTGYRESAAFLMRSADELENLLLQQQ 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG46301	NP_001334737.1	Integrase_H2C2	194..245	CDD:465569	36/50 (72%)
LOC1277782	XP_061518486.1	None