Protein Alignment nAChRalpha5 and HisCl1

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 88/353 - (24%)
• Similarity: 150/353 - (42%)
• Gaps: 56/353 - (15%)

  Fly   294 IFLLIYLN-LSAKV----CLAGY------------HEKRL-LHDLLD-PYNTLER---PVLNESD 336
            |.|.|||: |...:    |:.||            :|..| |.|:|. |..|.::   |.| ...
  Fly    15 IALAIYLHALEQSIQHCHCVHGYRNNTESAELVSHYESSLSLPDILPIPSKTYDKNRAPKL-LGQ 78

  Fly   337 PLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRW--NTSDYGGVKDLRIPPHRIWKPDV 399
            |..:.|.:|::.:..::|::...||:::|...|.|..||.  |.|:...:.|:.. .|.||:||.
  Fly    79 PTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDW-LHSIWRPDC 142

  Fly   400 LMYNSADEGFDGTYQTN--VVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDG 462
            ...|:....|......|  :.:.::.:.||:.......:|.:....:|.|.|.|.|...|.::
  Fly   143 FFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSH-- 205

  Fly   463 FQLDLQLQDETGGDI-------SSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITF---AII-- 515
                      |..|:       ...|:|.|.||..:....|  |...|...|....|   ||:
  Fly   206 ----------TVEDLVFIWNMTDPLVVNTEIELPQLDISNN--YTTDCTIEYSTGNFTCLAIVFN 258

  Fly   516 IRRRTLYYFFNLIIPCVLIASMALLGFTLPPDS-GEKLSLGVTILLSLTVFLNMVAETMPATSDA 579
            :|||..|:.|:..||..||..|:.:.|.:.|:: ..:::||||.||:|........:::|..| .
  Fly   259 LRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVS-Y 322

  Fly   580 VPLLGTYFNCIMFMVASSVVSTILILNY 607
            |..:..:.:.....|..|::...::.|:
  Fly   323 VKAIDVWMSSCSVFVFLSLMEFAVVNNF 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	79/317 (25%)
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	48/210 (23%)
		Neur_chan_memb	270..>350	CDD:280999	19/80 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100