Protein Alignment nAChRalpha5 and CG12344

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 76/350 - (21%)
• Similarity: 145/350 - (41%)
• Gaps: 56/350 - (16%)

  Fly   284 ILNGLNKHSWI-----FLLIYLNLSAKVCLAGYHEKRLLHDLLDPYNTLE-RPVLNESDPLQLSF 342
            :|:..|.:::|     |:|::|:.:.:..:....:.|:   :|.|....| ||...:..|:.:.|
  Fly     1 MLDKFNTNAFISFGLGFILMWLSEATEAHMNYTAKPRV---VLPPNYVKEIRPPSKKGSPVIVDF 62

  Fly   343 GLTLMQI-----IDVDEKNQLLVTNVWL--KLEWNDMNLRWNTSDYGGVKDLRIPP---HRIWKP 397
            .:.::.|     .|:|.:..:.:...||  :||..| ::.....||     :.:.|   ...|:|
  Fly    63 SIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPD-DIFEEGDDY-----VTLLPEVFENFWQP 121

  Fly   398 DVLMYNS-ADEGFDGTYQ-TNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTY 460
            |....|| ..|....|:: |:|.:..|.:..|.........|:::...:|.|.|.|.:...|::.
  Fly   122 DPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSS 186

  Fly   461 DGFQLDLQLQDETGGDISSYVLNGEWEL----LGVPGKRNEI--YYNCCPEP---YIDITFAIII 516
            :..::.|:..|      |...||.|.:|    ||.|.:..|.  |   .||.   :..:|.....
  Fly   187 NNQKVKLRWSD------SGVTLNPELKLLQYNLGQPLELEESDGY---MPEKVGNFSRLTVYFRF 242

  Fly   517 RRRTLYYFFNLIIPCVLIASMALLGFTLPPDS-GEKLSLGVTILLSLTVFLNMVAETMPATSDAV 580
            .|:..::......|..|:..::...|.|..|: ..:::|.||.:|:|.        ||...:|..
  Fly   243 ERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCMLTLV--------TMFTGADIP 299

  Fly   581 PLLGTYFNCIMFMVASSVVSTILIL 605
            |:  .|...:...:|..::|....|
  Fly   300 PV--AYVKALDLWMAGCMLSVFAAL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	69/315 (22%)
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	73/342 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100