Protein Alignment nAChRalpha5 and Lcch3

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_996469.1
• Gene: Lcch3 / 32554
• FlyBaseID: FBgn0010240
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 343
• Identity: 75/343 - (21%)
• Similarity: 137/343 - (39%)
• Gaps: 65/343 - (18%)

  Fly   295 FLLIYLNLSAKVC-----LAGYHEK--RLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQIIDV 352
            |.|:...|....|     |||..|.  :.:.::|..|:...||... .:||.:...||:.....:
  Fly    15 FFLLGAQLQLIRCIRKDVLAGRLENVTQTISNILQGYDIRLRPNFG-GEPLHVGMDLTIASFDAI 78

  Fly   353 DEKNQLLVTNVWLKLEWNDMNLRWNTSDYG---------GVKDLRIP----PHRIWKPDVLMYNS 404
            .|.|......::|...|.|..|.:|.  :|         |:.|:...    ..:||.||....|.
  Fly    79 SEVNMDYTITMYLNQYWRDERLAFNI--FGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFAND 141

  Fly   405 ADEGFDGTYQTNVVVR--NNGSCLYVPPGI-FKST--CKIDITWFPFDDQRCEMKFGSWTYDGFQ 464
            .:.......:.|.:||  .:|:..|   |: |.:|  |.:|:.::|.|.|.|.::..|:.|
  Fly   142 KNSFLHDVTERNKLVRLGGDGAVTY---GMRFTTTLACMMDLHYYPLDSQNCTVEIESYGY---- 199

  Fly   465 LDLQLQDETGGDISSYVLNGEWELLGVPG--------------KRNEIYYNCCPEPYIDITFAII 515
                    |..|:..|     |:...|.|              :.|:.........|..::.:..
  Fly   200 --------TVSDVVMY-----WKPTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFK 251

  Fly   516 IRRRTLYYFFNLIIPCVLIASMALLGFTLPPD-SGEKLSLGVTILLSLTVFLNMVAETMPATSDA 579
            ::|...|:.|...:|.:||..::.:.|.:..: :..:::||:|.:|::|.....|..::|..| .
  Fly   252 LQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRIS-Y 315

  Fly   580 VPLLGTYF-NCIMFMVAS 596
            |..:..|. .|.:|:.|:
  Fly   316 VKAIDIYLVMCFVFVFAA 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	68/320 (21%)
Lcch3	NP_996469.1	LIC	15..493	CDD:273305	75/343 (22%)
		Neur_chan_LBD	47..256	CDD:280998	48/231 (21%)
		Neur_chan_memb	263..490	CDD:280999	17/72 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447307
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030