Protein Alignment nAChRalpha5 and CG8916

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 390
• Identity: 84/390 - (21%)
• Similarity: 161/390 - (41%)
• Gaps: 67/390 - (17%)

  Fly   245 IAASTIAFISYLG-------------SFAAQLRSS-----------SSSSSNSSNSGN--SSSTQ 283
            :.:|.:.:|..:|             .|::::.||           :.|...|.|:.|  .||::
  Fly    24 VTSSDLLYIKTMGPSAILTKMPNITNEFSSRIFSSFRILPSSKPKTNGSLKRSQNATNLSYSSSE 88

  Fly   284 ILNGLNKHSWIFLLIYLNLSAKVCLAGYHEKRLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQ 348
            |.|...          :...|...:...:...:|.:||..|...:.|...:..|..:...:.:..
  Fly    89 ISNQRR----------VRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRS 143

  Fly   349 IIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIP---PHRIWKPDVLMYNSADEGFD 410
            :..|.|.:.....:.:.:..|.|..|.:.    |.:|.|.:.   ..:||:||...||.......
  Fly   144 MGPVSELDMDYSMDCYFRQYWRDKRLSFK----GPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIH 204

  Fly   411 GTYQTNVVVR--NNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQL--DLQLQD 471
            .....|.::|  .||..||......|:||.:::..||.|.|.|.:..||:.|...||  :.:.||
  Fly   205 MITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQD 269

  Fly   472 ETGGDISSYVLNGEWELLGVPGK-----RNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPC 531
            :....:....|| :::|:.:..:     |.|..::.       :..|..::|.|.|:...:.:||
  Fly   270 DAVSFVPGMTLN-QFDLISMMHRNFTTVRREGDFSV-------LHVAFNLKRHTGYFLIQVYVPC 326

  Fly   532 VLIASMALLGFTLPPD-SGEKLSLGVTILLSL-TVFLNMVAETMPATSDAVP----LLGTYFNCI 590
            :||..::.:.|.:..: :.:::||.||.:|:| |:.|:...: :|....|..    ||.::..||
  Fly   327 ILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTD-LPKVKYATALDWFLLMSFLYCI 390

  Fly   591  590
              Fly   391  390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	69/296 (23%)
CG8916	NP_573090.3	LIC	92..598	CDD:273305	70/322 (22%)
		Neur_chan_LBD	111..315	CDD:280998	48/215 (22%)
		Neur_chan_memb	322..>403	CDD:280999	19/70 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100