Protein Alignment nAChRalpha5 and CG6927

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 442
• Identity: 91/442 - (20%)
• Similarity: 163/442 - (36%)
• Gaps: 112/442 - (25%)

  Fly   315 RLLHDLLDPYNTLERPVLNESDPLQLSFGLTL------MQIIDVDEKNQLLVTNVWLKLEWNDMN 373
            ||.|..  .|:.||||:.......:|...:.:      ||.::..:    |...::..|:...::
  Fly    42 RLTHGC--RYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHD----LQFKIYALLQMRYLD 100

  Fly   374 LRWNTSDYG--------GVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPP 430
            .|.|..:..        |.:.||   :.:|.|.:.:.|..|....|..:.:::...:.....:..
  Fly   101 PRLNFRNVSPKRRQPILGEEHLR---NSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVS 162

  Fly   431 GIFKST--CKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDE-----TGG-DISSYVLNGEW- 486
            ...|:|  |.:::..||||:|.|.....||.|:..:|.|..:.:     .|. .::.:||...|
  Fly   163 NRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWS 227

  Fly   487 -ELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSG- 549
             |.: :....:::.:......|..::|.:.:.|...:|..:..:|.:||.:::.:.|.|..|..
  Fly   228 NETV-INADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAP 291

  Fly   550 EKLSLGVTILLSLTVFLNMVAETMPATS----DAVPLLGTYFNCIMFMVASSV----VSTILILN 606
            .:::||.:.||:.....:...:|:|..|    ..|..||    |.:|:..|.|    |:||
  Fly   292 PRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLG----CTIFIFGSMVEFAFVNTI---- 348

  Fly   607 YHHRNADTHEMSEWIRIVFLCWLPWILRMSRPGRPLILEFPTTPCSDTSSERKHQILSDVELKER 671
                                    |..:.|.|.:.|              ..||      .||..
  Fly   349 ------------------------WRRKKSVPVKKL--------------NSKH------ILKST 369

  Fly   672 SSKSLLANVLDIDDDFRHNCRPMTPGGTLPHNPAFYRTVYGQGDDGSIGPIG 723
            .|.:||..        |.:.|..:..||..|..|         |.||:|..|
  Fly   370 LSPNLLRR--------RSHARSRSFSGTALHKTA---------DTGSLGGAG 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	91/442 (21%)
CG6927	NP_572194.1	LIC	3..520	CDD:273305	91/442 (21%)
		Neur_chan_LBD	36..259	CDD:280998	44/226 (19%)
		Neur_chan_memb	270..518	CDD:280999	45/204 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447259
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030