Protein Alignment nAChRalpha5 and pbo-6

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_001294833.1
• Gene: pbo-6 / 24104421
• WormBaseID: WBGene00017375
• Length: 422
• Species: Caenorhabditis elegans
• Alignment Length: 347
• Identity: 103/347 - (29%)
• Similarity: 178/347 - (51%)
• Gaps: 24/347 - (6%)

  Fly   295 FLLIYLNL-SAKVCLAGYHEK------RLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQIIDV 352
            ||.|::.: :..|.:|.:.|:      ||...||:.:|....|    ...:.:|..:.|:.||.:
 Worm     5 FLTIFIFITTVTVGVAEFSEQYQGSSSRLTRHLLEKHNKCSPP----DGRVDISHNIELVHIIGI 65

  Fly   353 DEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSAD-EGFDGTYQTN 416
            :|.||.:...|::..:|.|.:|.|...::.|:|...:|.|.||.||::::|:.: :......::.
 Worm    66 NELNQNMQVLVYIVQQWTDASLSWKVEEFRGIKHTWLPEHSIWIPDIIVFNTLEHKMLLEAVRSP 130

  Fly   417 VVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYV 481
            :.|...|...|..|.|:...|:|.|..||||||.|:::|.||.||..::.|....:.  .:.:|.
 Worm   131 IKVSYTGEVTYAYPAIYTVLCQIGIATFPFDDQVCKIRFASWAYDEDKILLNASHKP--LLKNYS 193

  Fly   482 LNGEWELLGVPGKRNEIYYNCCPEPYI-DITFAIIIRRRTLYYFFNLIIPCVLIASMALLG---- 541
            .|.||.|..|...|.|..:.   |..: :|.:.|.:.|:..||..:|::|..:|..:::.|
 Worm   194 PNEEWALQDVDMARKEYEHE---ETVVSEIIYYIKVARKPFYYLISLVVPSYIICVLSIAGLFAR 255

  Fly   542 FTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILN 606
            |:...:..|:.:||||.:||:.|...:|.|.:|.:|:.||||..|.:.|:.||..:.:.|..::.
 Worm   256 FSTKHERQERFTLGVTAILSMAVLSLVVTEKVPHSSENVPLLIVYMHFIIVMVTIATILTSTVMR 320

  Fly   607 YHHRNADTHEMS--EWIRIVFL 626
            .|.:...||.:|  .|||.|.|
 Worm   321 VHAKGFRTHFLSPPNWIRKVLL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	98/328 (30%)
pbo-6	NP_001294833.1	Neur_chan_LBD	31..230	CDD:280998	60/207 (29%)
		Neur_chan_memb	264..>342	CDD:280999	29/77 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010