Protein Alignment nAChRalpha5 and lgc-11

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: NP_509270.1
• Gene: lgc-11 / 181009
• WormBaseID: WBGene00000061
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 339
• Identity: 94/339 - (27%)
• Similarity: 167/339 - (49%)
• Gaps: 37/339 - (10%)

  Fly   312 HEKRLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRW 376
            :|:.|...|||.|....|||.|.|..|.::....:..:::|:|:|:.:...:|....|.|..|.|
 Worm    35 NERELAKHLLDDYYQYTRPVRNYSSVLNVTVQPQIYNLVEVNEQNEQIKILLWFPQSWKDDYLTW 99

  Fly   377 NTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDI 441
            :..::.|::.:.||..:||.||..::|:.:| .:.....|..||.:|........:...||.:.:
 Worm   100 DPKEWNGIERIIIPKSQIWIPDGYIFNTVEE-TEPLENHNARVRYDGRVEVDFNKLVDLTCPMSV 163

  Fly   442 TWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYY------ 500
            ..||||.|.|.::||||:|....:...:.|..   :.....|.||:::.....:....|
 Worm   164 LSFPFDVQLCALQFGSWSYQAHAISFNVLDTF---VPKKSKNSEWDIVSFNATKMTTKYGDTLGG 225

  Fly   501 -NCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLP----PDSGEKLSLGVTILL 560
             |.    |.:|.:.:.:||:.|||...:::|..||.:::.:|...|    .|..|.:|||:|.:|
 Worm   226 FNV----YEEIFYYLELRRKPLYYIVVILLPSFLIVTVSNIGLFTPHGVHGDREEHVSLGLTTML 286

  Fly   561 SLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVA--SSVVSTILILNYHHRNADTHEMSEWIRI 623
            ::.|.|:||...||.:|:.:||||.|. .|.|:::  :.:||.::|.        .||     |:
 Worm   287 TMAVILDMVTGQMPRSSEGIPLLGMYV-LIEFVISVIAVLVSVVIIF--------AHE-----RM 337

  Fly   624 VFLCWLP--WILRM 635
            ::|...|  |:.::
 Worm   338 LYLDATPPYWVCKL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	94/338 (28%)
lgc-11	NP_509270.1	Neur_chan_LBD	36..242	CDD:280998	56/213 (26%)
		Neur_chan_memb	249..>336	CDD:280999	31/100 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010