Protein Alignment nAChRalpha5 and LOC100487782

DIOPT Version :9

• Sequence 1: NP_001356885.1
• Gene: nAChRalpha5 / 34826
• FlyBaseID: FBgn0028875
• Length: 837
• Species: Drosophila melanogaster
• Sequence 2: XP_031759268.1
• Gene: LOC100487782 / 100487782
• -ID: -
• Length: 512
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 240/522 - (45%)
• Similarity: 338/522 - (64%)
• Gaps: 46/522 - (8%)

  Fly   293 WIFLLIYLNLSAKVCLAGYHEKRLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQ 357
            |||:::.|...:.   .|.::::|..:||..||.|||||:|:|.||.:...|||:||||||||||
 Frog    17 WIFVILTLPGGSH---QGQYQRKLYRELLRNYNRLERPVVNDSQPLLVELQLTLLQIIDVDEKNQ 78

  Fly   358 LLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNN 422
            :|:||.||::.|||..|.|:.::|.||:.||.|...||.||:|:||||||.||.|:.|||:|.:.
 Frog    79 VLITNAWLQITWNDFYLTWDQAEYPGVQTLRFPADHIWVPDILLYNSADERFDATFHTNVLVNST 143

  Fly   423 GSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWE 487
            |:|.|:||||.||||.||:.|||||.|:|::||||||::|:.||||:.:   .|||||:.||||:
 Frog   144 GACQYIPPGILKSTCYIDVRWFPFDVQKCKLKFGSWTHNGWLLDLQMME---ADISSYIPNGEWD 205

  Fly   488 LLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKL 552
            |:||||||||:||.||.|||.|:|:.:.:|||||||..||:||||||:.:|||.|.||.|||||:
 Frog   206 LVGVPGKRNELYYECCKEPYPDVTYTVTMRRRTLYYGLNLLIPCVLISGLALLVFLLPADSGEKI 270

  Fly   553 SLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEM 617
            |||:|:|||||||:.:|||.||||||:|||:..||..||.:|..|||.|:|:|.:||.:....:|
 Frog   271 SLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASIMVIVGLSVVVTVLVLQFHHHDPQAGKM 335

  Fly   618 SEWIRIVFLCWLPWILRMSRPG---RPLILEFPTTPCSDTSSERKHQILSDVELK-ERSSKSLLA 678
            .:.:|::.|.|..|.|||.:||   ||:       ||....... |..:|.:|:. ....:|...
 Frog   336 PKMVRVILLNWCAWFLRMRKPGENKRPI-------PCKYIYPNH-HSSISSIEMNIAPGHQSTNG 392

  Fly   679 NVLDIDDDFRHN-----CRPMTPGGTLPHNPAFYRTVYGQGDDGSIGPIGSTRMPDA-VTHHTCI 737
            |::...   .|.     |.|.:..|.:                  ...:....:.|: :.....:
 Frog   393 NIVYCG---YHTLESPCCPPNSDSGVM------------------CARVNCPSLEDSDLIQKKSL 436

  Fly   738 KSSTEYELGLILKEIRFITDQLRKDDECNDIANDWKFAAMVVDRLCLIIFTMFTILATIAVLLSA 802
            |.|.. |:..||:|:::|..:.|:.|...:|.::|||||.|:|||||:.|::|.|:||..:|:||
 Frog   437 KESMP-EIVKILEEVQYIARRFREQDAGEEICSEWKFAAAVIDRLCLVAFSLFAIIATFTILMSA 500

  Fly   803 PH 804
            |:
 Frog   501 PN 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha5	NP_001356885.1	LIC	313..802	CDD:273305	232/498 (47%)
LOC100487782	XP_031759268.1	LIC	16..500	CDD:273305	237/518 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1510
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	502	1.000	Inparanoid score	I1318
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D363540at33208
OrthoFinder	1	1.000	-	-		FOG0000891
OrthoInspector	1	1.000	-	-		mtm9339
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3025
SonicParanoid	1	1.000	-	-		X767
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.000