DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC4 and SCARF2

DIOPT Version :9

Sequence 1:	NP_609698.2	Gene:	NimC4 / 34824	FlyBaseID:	FBgn0260011	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_699165.3	Gene:	SCARF2 / 91179	HGNCID:	19869	Length:	871	Species:	Homo sapiens

Alignment Length:	309	Identity:	79/309 - (25%)
Similarity:	99/309 - (32%)	Gaps:	103/309 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 CCPGYLQVESGLCEPICSRGCPAHASCAAPDR-CECISGYVSARNHQ-DGSHYCEP-----ICET 134
            |.....:.:||.|:      |......|..|| |:|..|    |.|. ||:..|||     .|..
Human   217 CNSSPCEQQSGRCQ------CRERTFGARCDRYCQCFRG----RCHPVDGTCACEPGYRGKYCRE 271

  Fly   135 PCPAG----------AQCVTPNTC--------ACRDGYTQL---QPTDDGVSG-GCA---PVCRV 174
            |||||          .||.....|        .|..|:...   ||...|..| ||:   |.||.
Human   272 PCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRD 336

  Fly   175 GDGC--ANGKCIDVDRCACNSGYRWDKAEERCIELSAESISEELETTEDNTDSPSTSSTAVFTAT 237
            |..|  ..|||     ..||:|:..|:.|.:|   |..:..|:                ..|...
Human   337 GHACNHVTGKC-----TRCNAGWIGDRCETKC---SNGTYGED----------------CAFVCA 377

  Fly   238 HCPDDFVLFRGECREKQFDSNDVGCLKSGCGPHQTCLDSGVCQ--CSDGYVPEESGEATGVLSCR 300
            .|..      |.|   .|.|....|.....|||        |.  |..|....:..:|   .||.
Human   378 DCGS------GHC---DFQSGRCLCSPGVHGPH--------CNVTCPPGLHGADCAQA---CSCH 422

  Fly   301 RTLLDQILGLNEAIDDDDELNPWTIPIIGV-ACGFLFVLLI---VGLLG 345
            ....|.:.|......:..:         || ..|.|.|||:   :.|||
Human   423 EDTCDPVTGACHLETNQRK---------GVMGAGALLVLLVCLLLSLLG 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
NimC4	NP_609698.2	None
SCARF2	NP_699165.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		PHA03247	<534..871	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	570..871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900