Protein Alignment NimC4 and MEGF11

DIOPT Version :10

• Sequence 1: NP_609698.2
• Gene: NimC4 / 34824
• FlyBaseID: FBgn0260011
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_001371957.1
• Gene: MEGF11 / 84465
• HGNCID: 29635
• Length: 1140
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 82/382 - (21%)
• Similarity: 115/382 - (30%)
• Gaps: 154/382 - (40%)

  Fly     6 ALILVLGSIAANAERDNYCERNETIRATVPVTK----QRIIVKQPSKWKIWKKTEKITEIYDSEE 66
            |...:..::|.|.|..|.|...|:...||..:.    .:|...:.:....|.|..:....|.:..
Human    10 AFSFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAY 74

  Fly    67 EQVTHRLVR---ECCPGYLQVESG-LCEPICSRGCPAHASCAAPDRCECISGY--VSARNHQDGS 125
            .:....:.|   :|||||  .||| .|.|:|:..| .|..|.:||.|.|..|:  ....:..|..
Human    75 RRGLRTMYRRRSQCCPGY--YESGDFCIPLCTEEC-VHGRCVSPDTCHCEPGWGGPDCSSGCDSD 136

  Fly   126 HY---------------CEPI---------------------------CETPCPA--GAQCVTPN 146
            |:               |.||                           |:.||..  ||.| .|.
Human   137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASC-DPR 200

  Fly   147 T--CACRDGYTQLQ------------------PTDDG-----VSGGCA-------PVC------- 172
            .  |.|..|||.:.                  |..:|     ::|.||       .||
Human   201 AGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPG 265

  Fly   173 RVGDGCA-------NGKCIDV-DRCACNSGYRWDKAEERCIELSAESISEELETTEDNTDSPSTS 229
            ..|..|:       .|:|..| .:|.|.:||..|:.:|.|
Human   266 TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEEC------------------------- 305

  Fly   230 STAVFTATHCPDDFVLFRGECREKQFDSNDVGCLKSG-CGPHQTCLDSGVCQCSDGY 285
                        .|..|..:|      |....|...| |.|     .:|.|:|..||
Human   306 ------------PFGSFGFQC------SQHCDCHNGGQCSP-----TTGACECEPGY 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC4	NP_609698.2	None
MEGF11	NP_001371957.1	EMI	25..94	CDD:462204	15/70 (21%)
		EGF_CA	275..320	CDD:473889	14/87 (16%)
		EGF_CA	362..409	CDD:473889