DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC4 and pear1

DIOPT Version :9

Sequence 1:	NP_609698.2	Gene:	NimC4 / 34824	FlyBaseID:	FBgn0260011	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_700533.4	Gene:	pear1 / 571812	ZFINID:	ZDB-GENE-091230-1	Length:	1020	Species:	Danio rerio

Alignment Length:	362	Identity:	87/362 - (24%)
Similarity:	116/362 - (32%)	Gaps:	114/362 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IWALILVLG-----SIAANAERDNYCERNETIRATVPVTKQRIIVKQP----------SKWKIWK 53
            |..::.|||     |::.:....|.|...|:...:|..:     ..||          ..|...|
Zfish     6 ICVVLFVLGCVCELSLSLDPRDPNVCSLWESFTTSVKES-----YAQPFDQMSEEPCSEPWSANK 65

  Fly    54 KT-EKITEIYDSEEEQVT---HRLVRECCPGYLQVESGLCEPICSRGCPAHASCAAPDRCECISG 114
            .| .:||  |.:...||.   :|...:||||:.: ....|.|.|::.| .|..|.|||||:|..|
Zfish    66 CTRHRIT--YKTLYRQVVKMDYRRRYQCCPGFYE-SRNKCVPRCTKEC-VHGRCVAPDRCQCEMG 126

  Fly   115 Y--VSARNHQDGSHY---CEPICETPCPAGAQC-VTPNTCACRDGYTQLQPTD----DGVSGGCA 169
            :  ....:..||.|:   |..:||  |..|.:| |....|.|..|||.....|    .....||.
Zfish   127 WRGDDCSSSCDGQHWGPGCRRLCE--CQNGGECDVLTGNCQCPAGYTGQHCHDPCPVKWFGQGCR 189

  Fly   170 PVCRVGDGCANGKCID-VDRCACNSGYRWDKAEERCIELSAESISEELETTEDNTDSPSTSSTAV 233
            ..|:.|.|   |.|.. ...|.|..|:.....||.|                     |....
Zfish   190 QECQCGTG---GICNQTTGECVCKQGFTGTLCEESC---------------------PRPKR--- 227

  Fly   234 FTATHCPDDFVLFRGECREKQFDSNDVGCL-----------------KSGCGPHQTCL------- 274
             .|..||         |:.......:..||                 :.|....:.||
Zfish   228 -CAARCP---------CQNGGICQGNGVCLCPPGWMGPVCTERCPPGRFGINCSKDCLCHNGGHC 282

  Fly   275 --DSGVCQCSDGYVPEESGE----------ATGVLSC 299
              :.|.|||..||..|...|          ..||..|
Zfish   283 DQEKGQCQCDAGYTGERCNEECPVGTYGEDCKGVCDC 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC4	NP_609698.2	None
pear1	XP_700533.4	EMI	29..96	CDD:284877	19/73 (26%)
pear1	XP_700533.4	Laminin_EGF	411..451	CDD:278482
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810