DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC4 and Dkk4

DIOPT Version :9

Sequence 1:	NP_609698.2	Gene:	NimC4 / 34824	FlyBaseID:	FBgn0260011	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_663567.1	Gene:	Dkk4 / 234130	MGIID:	2385299	Length:	221	Species:	Mus musculus

Alignment Length:	158	Identity:	34/158 - (21%)
Similarity:	49/158 - (31%)	Gaps:	40/158 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 YDSEEEQVTHRLVRE-------CCPGYLQVESGLC------EPICSRGCPAHASCAAPDRCECIS 113
            :|......|.|.||.       ||||.:.| :.:|      .|:..|.........|    |..:
Mouse    57 HDERSFCATCRRVRRRCQRSAVCCPGTVCV-NDVCTAVEDTRPVMDRNTDGQDGAYA----EGTT 116

  Fly   114 GYVSARNHQDGSHYCEPICETPCPAGAQCVT-----PNTCACRDGYTQLQPTDDGVSGGCAPVCR 173
            .:.:..|...|....:....:....|..|:.     |..|..|..:|::          |.||.|
Mouse   117 KWPAEENRPQGKPSTKKSQSSKGQEGESCLRTSDCGPGLCCARHFWTKI----------CKPVLR 171

  Fly   174 VGDGCANGKCIDV-------DRCACNSG 194
            .|..|:.....|.       .||.|..|
Mouse   172 EGQVCSRRGHKDTAQAPEIFQRCDCGPG 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC4	NP_609698.2	None
Dkk4	NP_663567.1	Dickkopf_N	41..91	CDD:368068	10/34 (29%)
		DKK-type Cys-1	41..90		10/33 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..143		5/45 (11%)
		DKK-type Cys-2	145..218		16/65 (25%)
		Prokineticin	<145..202	CDD:148298	16/65 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900