DRSC/TRiP Functional Genomics Resources

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Protein Alignment NimC4 and DKK1

DIOPT Version :9

Sequence 1:NP_609698.2 Gene:NimC4 / 34824 FlyBaseID:FBgn0260011 Length:377 Species:Drosophila melanogaster
Sequence 2:NP_036374.1 Gene:DKK1 / 22943 HGNCID:2891 Length:266 Species:Homo sapiens


Alignment Length:237 Identity:58/237 - (24%)
Similarity:78/237 - (32%) Gaps:76/237 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 GCPAHASCAAPDRCECISGYVSARNHQDGSHYCEPICETPCPAGAQCVTPNTCACRDGYTQLQPT 160
            |.|..|..|||...     |.....:|...:| :|.   ||....:|.|...||        .||
Human    54 GHPGSAVSAAPGIL-----YPGGNKYQTIDNY-QPY---PCAEDEECGTDEYCA--------SPT 101

  Fly   161 DDGVSG-----GCA---------PVCRVGDGCANGKCIDVDRCACNSGYRWDKAEERCIELSAES 211
            ..|.:|     .|.         .:|..|:.|.||.|:..|:    :.:|.:      ||   |:
Human   102 RGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQ----NHFRGE------IE---ET 153

  Fly   212 ISEELETTEDNTDSPSTSSTAVFTATHC--PDDFVLFR------GECREKQFDSNDVGC---LKS 265
            |:|.........|..|..:|......|.  .:..|..|      |.|..:.|.|..  |   ||.
Human   154 ITESFGNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKI--CKPVLKE 216

  Fly   266 G--CGPHQTCLDSGV-----CQCSDGYVPEESGEATGVLSCR 300
            |  |..|:.....|:     |.|.:|            ||||
Human   217 GQVCTKHRRKGSHGLEIFQRCYCGEG------------LSCR 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NimC4NP_609698.2 None
DKK1NP_036374.1 Dickkopf_N 85..139 CDD:309719 15/61 (25%)
DKK-type Cys-1 85..138 15/60 (25%)
DKK-type Cys-2 189..263 19/72 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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