DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC4 and Scarf2

DIOPT Version :9

Sequence 1:	NP_609698.2	Gene:	NimC4 / 34824	FlyBaseID:	FBgn0260011	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_036015777.1	Gene:	Scarf2 / 224024	MGIID:	1858430	Length:	838	Species:	Mus musculus

Alignment Length:	341	Identity:	79/341 - (23%)
Similarity:	109/341 - (31%)	Gaps:	132/341 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 CCPGYLQVE---------SGLCEP-----IC-----SRGCPAHASC-AAP-----DRCECISGYV 116
            |.||:...:         :..|:|     :|     .|.|....:| ::|     .||:|.....
Mouse   164 CEPGWWGAQCASACYCSATSRCDPQTGACLCHVGWWGRSCNNQCACNSSPCEQQSGRCQCRERMF 228

  Fly   117 SAR-------NH-----QDGSHYCEP-----ICETPCPAG----------AQCVTPNTC------ 148
            .||       :|     .||:..|:|     .|..|||||          .||.....|
Mouse   229 GARCDRYCQCSHGRCHPVDGTCACDPGYRGKYCREPCPAGFYGPGCRRRCGQCKGQQPCTVVEGR 293

  Fly   149 --ACRDGYTQL---QPTDDGVSG-GC---APVCRVGDGC--ANGKCIDVDRCACNSGYRWDKAEE 202
              .|..|:...   ||...|..| ||   .|.||.|..|  ..|||..     ||:|:..|:.|.
Mouse   294 CLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTH-----CNAGWIGDRCET 353

  Fly   203 RCIELSAESISEELETTEDNTDSPSTSSTAVFTATHCPDDFVLFRGECREKQFDSNDVGCLKSGC 267
            :|   |..:..|:                ..|..:.|..      |.|   .|.|....|.....
Mouse   354 KC---SNGTYGED----------------CAFVCSDCGS------GHC---DFQSGRCLCSPGVH 390

  Fly   268 GPH--QTC------LD-SGVCQCSD-------GYVPEESGEATGVLSCRRTLLDQILGLNEAIDD 316
            |||  .||      :| :..|.|.:       |....|:.:..||:.. ..||..:|||
Mouse   391 GPHCNVTCPAGLHGVDCAQACSCHEESCDPVTGACHLETNQRKGVMGA-GALLTLLLGL------ 448

  Fly   317 DDELNPWTIPIIGVAC 332
                   .:.::|..|
Mouse   449 -------LLSLLGCCC 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC4	NP_609698.2	None
Scarf2	XP_036015777.1	exchanger_TraA	<74..431	CDD:411343	70/299 (23%)
		PHA03307	526..>836	CDD:223039
		PHA03247	<683..838	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900