DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NimC4 and CCBE1

DIOPT Version :9

Sequence 1:NP_609698.2 Gene:NimC4 / 34824 FlyBaseID:FBgn0260011 Length:377 Species:Drosophila melanogaster
Sequence 2:XP_016881045.1 Gene:CCBE1 / 147372 HGNCID:29426 Length:435 Species:Homo sapiens


Alignment Length:425 Identity:88/425 - (20%)
Similarity:128/425 - (30%) Gaps:162/425 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LILVLGSIAANAERDNYCERNETIRATVPVTKQRIIVKQPSKWKIWKKTEKITEIYDSEEEQVTH 71
            |:|.||......|.....:|.....:.:..|          |:...|.:.::|..|.        
Human    25 LLLALGHTWTYREEPEDGDREICSESKIATT----------KYPCLKSSGELTTCYR-------- 71

  Fly    72 RLVRECCPGYLQVESGLCEP----ICSRGCPAHASCAAPDR-----CECISG--YVSARNHQDGS 125
               ::||.||..| .|.|.|    :|:. .|....|.  |.     |.|..|  |...|:.:...
Human    72 ---KKCCKGYKFV-LGQCIPEDYDVCAE-APCEQQCT--DNFGRVLCTCYPGYRYDRERHRKREK 129

  Fly   126 HYCEPICETPCPAGAQC--VTPNT-----CACRDGYTQLQPTDDGVSGGCAPVCRVGDGCAN--- 180
            .||..|.|.....|..|  :..||     |.||:||.:   .|||      ..|..||...|   
Human   130 PYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIR---EDDG------KTCTRGDKYPNDTG 185

  Fly   181 ----------GKCIDVDRCA-CNSGYRWDKAEERCIELSAESISEELETTEDNTDSPS---TSST 231
                      |.|     || |...|:        ::.:...:.:::....:|.....   |...
Human   186 HEKSENMVKAGTC-----CATCKEFYQ--------MKQTVLQLKQKIALLPNNAADLGKYITGDK 237

  Fly   232 AVFTATHCPDDFVLFRGECREKQFDSNDVGCLKSGCGPHQTCLDSGVCQCSDGYVPEESGEA-TG 295
            .:.:.|:.|                 ...| |..|.||                 |.|.|.. ..
Human   238 VLASNTYLP-----------------GPPG-LPGGQGP-----------------PGECGRGHRR 267

  Fly   296 VLSCRRTL--------LDQILGL----NEAIDDDDEL-------------------NPW----TI 325
            |::.|::|        ||.:|.|    |:|..|..|.                   :||    ..
Human   268 VITNRKSLPKAHICWGLDNVLQLPSRRNKAHQDQREAQASPVCQALLGSPAHGAQWDPWDHLLIC 332

  Fly   326 PIIGVACGFLFVLLIVGLLGGRRYRQERAALANKE 360
            |.:..|.|.|:|         .:..||...|..:|
Human   333 PTLSKAGGALWV---------HQGHQEEMVLRGRE 358



Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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