DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NimC4 and ESM1

DIOPT Version :9

Sequence 1:NP_609698.2 Gene:NimC4 / 34824 FlyBaseID:FBgn0260011 Length:377 Species:Drosophila melanogaster
Sequence 2:NP_008967.1 Gene:ESM1 / 11082 HGNCID:3466 Length:184 Species:Homo sapiens


Alignment Length:183 Identity:38/183 - (20%)
Similarity:52/183 - (28%) Gaps:69/183 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 CPGYLQVESGLCEPICSR------GCPAHASCAAPDRC-ECISGYVSARNHQDGSH-----YCEP 130
            ||.:.........|.|.|      ||....:....:.| ..:||       .||..     .|:|
Human    28 CPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSG-------MDGMKCGPGLRCQP 85

  Fly   131 ------------ICETPCPAGA---QCVTPNTCACRDGYTQLQPTDDGVSGGCAPVCRVGDGCAN 180
                        ||: .||.|.   .|  ..||.|:.|                 :|..|    .
Human    86 SNGEDPFGEEFGICK-DCPYGTFGMDC--RETCNCQSG-----------------ICDRG----T 126

  Fly   181 GKCIDVDRCACNSGYRWDKAEERCIELSAE-------SISEELETTEDNTDSP 226
            |||:......    |...|:..|.:.|:..       :|..|....|:...||
Human   127 GKCLKFPFFQ----YSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSP 175

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NimC4NP_609698.2 None
ESM1NP_008967.1 IB 26..100 CDD:197525 15/78 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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