DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimC4 and pear1

DIOPT Version :9

Sequence 1:	NP_609698.2	Gene:	NimC4 / 34824	FlyBaseID:	FBgn0260011	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_017952446.2	Gene:	pear1 / 100489801	XenbaseID:	XB-GENE-6045593	Length:	1087	Species:	Xenopus tropicalis

Alignment Length:	330	Identity:	82/330 - (24%)
Similarity:	124/330 - (37%)	Gaps:	73/330 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IWALILVLGSIAANAERDNYCERNETIRATVPVTKQRIIVKQP----------SKWKIWKKTEKI 58
            :|.|:.:....:.:....|.|...|:....|..:     ..||          |.|..:|.....
Frog    11 VWMLVQIQFGKSLSPNDPNVCSFWESFTLAVKES-----YTQPYSQLSPDSCDSSWNYFKACTPQ 70

  Fly    59 TEIYDSEEEQVTHRLVRE------CCPGYLQVESGLCEPICSRGCPAHASCAAPDRCECISGYVS 117
            ..:|   .....||:..:      ||.||.: .:.:|.|.|::.| .|..|.|||:|:|..|:
Frog    71 KILY---RTAYRHRVKLDYRRRYWCCKGYYE-SNDICVPRCTQEC-VHGRCIAPDQCQCEPGW-- 128

  Fly   118 ARNHQDGSHYCE-----PICETPCPA---GAQCVTPNTCAC----RDGYTQLQPTDDGV-SGGCA 169
              ..:|.|..||     |.|.:.||.   ||......||.|    ||.:.: :|.|.|. .|||:
Frog   129 --RGKDCSSACEAHVWGPKCNSTCPCQNNGACDAASGTCICPPGFRDPFCE-KPCDPGTYGGGCS 190

  Fly   170 PVCRVGDGCANGKCIDVDR--CACNSGYRWDKAEERCIELSAE--SISEELETTEDNTDSPSTSS 230
            ..|:    |.||...|.:.  |.|..||.....|.||.|:...  |.|::.........:.|:..
Frog   191 LSCQ----CKNGAECDPENGACLCPEGYTGPYCEIRCKEVQPANFSCSDQCLCQSGGICNQSSGE 251

  Fly   231 TAV-------FTATHCPDDFVLFRGECREKQFDSNDVGCLKSG-CGPHQTCLDSGVCQCSDGYVP 287
            .:.       ..:..|||.:  :...|:::..      |...| |.|     .:|.|.||:||..
Frog   252 CSCPPGWMGSLCSIPCPDGY--YGRNCKQECL------CHNGGQCDP-----KTGQCLCSEGYTG 303

  Fly   288 EESGE 292
            :...|
Frog   304 DHCRE 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC4	NP_609698.2	None
pear1	XP_017952446.2	EMI	29..97	CDD:400092	15/75 (20%)
		exchanger_TraA	<147..>310	CDD:411343	46/180 (26%)
		exchanger_TraA	<416..729	CDD:411343
		Laminin_EGF	546..586	CDD:395007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910