DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC4 and Stab1

DIOPT Version :9

Sequence 1:	NP_609698.2	Gene:	NimC4 / 34824	FlyBaseID:	FBgn0260011	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_008769275.1	Gene:	Stab1 / 100363145	RGDID:	2324745	Length:	2630	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	72/280 - (25%)
Similarity:	95/280 - (33%)	Gaps:	102/280 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 VRECCPGYLQVESGLCEPICSRG----CPAHASCAAPDR------CECISGYVSARNHQDGSHYC 128
            |.:||||:.   ..|||| |..|    |..|..|  .||      |.|..|:     |......|
  Rat  1377 VPDCCPGFF---GTLCEP-CPGGLGGVCSGHGQC--QDRFLGNGECRCQEGF-----HGTACEMC 1430

  Fly   129 E-----PICETPCPAGAQCVTPNTCACRDGYTQLQPTDDGVSGGCAPVCRVG------------- 175
            |     |.|.            ..|.|..|..|     :|:.|..:.:|.||
  Rat  1431 ELGRYGPTCS------------GVCDCDHGLCQ-----EGLRGNGSCICNVGWQGLRCDQKITDR 1478

  Fly   176 ---DGC-ANGKCID----VDRCACNSGYRWDKAEERCIELSAESISEELE--TTEDNTDSPSTSS 230
               ..| .|..||.    :..|.|.:||..:           .|...|::  |:.....||..:.
  Rat  1479 QCPKKCDPNANCIQDSAGIPVCVCAAGYSGN-----------GSYCSEVDPCTSGHGGCSPYANC 1532

  Fly   231 TAVF----TATHCPDDFVLFRGECREKQFDSNDVGCL--KSGCGPHQTCLDSG----VCQCSDGY 285
            |.|.    |.| |.|.:......|:|..      .||  ..||..:..|:.:|    .|.|.:||
  Rat  1533 TKVAPGQRTCT-CLDGYTGDGELCQEIN------SCLVHNGGCHVNAECIPTGPQQVSCNCREGY 1590

  Fly   286 VPEESGEATGVLSCRRTLLD 305
                ||:  |:.||:  |||
  Rat  1591 ----SGD--GIQSCK--LLD 1602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC4	NP_609698.2	None
Stab1	XP_008769275.1	Fasciclin	391..494	CDD:295423
		Fasciclin	523..647	CDD:280607
		EGF_3	834..863	CDD:289699
		EGF_3	918..949	CDD:289699
		EGF_3	955..991	CDD:289699
		Fasciclin	<1100..1180	CDD:280607
		Fasciclin	1224..1313	CDD:295423
		EGF_3	1519..1555	CDD:289699	9/36 (25%)
		EGF_3	1561..1595	CDD:289699	12/39 (31%)
		EGF_3	1604..1641	CDD:289699
		Fasciclin	1666..1770	CDD:280607
		Fasciclin	1796..1926	CDD:280607
		EGF_Lam	2037..2082	CDD:238012
		EGF_3	2154..2189	CDD:289699
		EGF_3	2195..2232	CDD:289699
		Link_Domain	2267..2359	CDD:295393
		FAS1	2426..2521	CDD:214719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900