DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18095 and FLS2

DIOPT Version :9

Sequence 1:	NP_001188805.1	Gene:	CG18095 / 34823	FlyBaseID:	FBgn0028872	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001330009.1	Gene:	FLS2 / 834676	AraportID:	AT5G46330	Length:	1173	Species:	Arabidopsis thaliana

Alignment Length:	683	Identity:	160/683 - (23%)
Similarity:	233/683 - (34%)	Gaps:	228/683 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 LSNCTLPHVENGFFVRFDHLLHLELQHSGLSDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPL 110
            :.||:             .|:.|||..:.|:......|..|.:||.|.:..|.|:|....|...|
plant   260 IGNCS-------------SLVQLELYDNQLTGKIPAELGNLVQLQALRIYKNKLTSSIPSSLFRL 311

  Fly   111 GALTNLDLSHN-----------MLSKLSVKSFE------QYPQ-------LQQLDLRYNRIS--- 148
            ..||:|.||.|           .|..|.|.:..      ::||       |..|.:.:|.||
plant   312 TQLTHLGLSENHLVGPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTVGFNNISGEL 376

  Fly   149 --------QIEN-------------DSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQH 192
                    .:.|             .|....:.||.|.|:.||:.   |...||..|::...:..
plant   377 PADLGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMT---GEIPRGFGRMNLTFISI 438

  Fly   193 NRIEF---IEMDSFE-SNTH-------------------LRSLRLDQNLLSSLQFLSQRGLARLV 234
            .|..|   |..|.|. ||..                   |:.||:.|...:||.....|.:..|.
plant   439 GRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLIGKLQKLRILQVSYNSLTGPIPREIGNLK 503

  Fly   235 HLN---LSSN--------------LLQKLEPFVFSKNFE------------LQDLDLSYNNITKL 270
            .||   |.||              |||.|.  ::|.:.|            |..||||.|..:..
plant   504 DLNILYLHSNGFTGRIPREMSNLTLLQGLR--MYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQ 566

  Fly   271 NKEALSGLDSLERLNISHNYVDKIYDESLDSLIALLQLDISFNLLT-TLPDNLFHF--NTQLEEI 332
            .....|.|:||..|::..|..:.....||.||..|...|||.|||| |:|..|...  |.|| .:
plant   567 IPALFSKLESLTYLSLQGNKFNGSIPASLKSLSLLNTFDISDNLLTGTIPGELLASLKNMQL-YL 630

  Fly   333 ILANNKIEEISSQMMFNQNHLRYIKLSGNAISDAAFLDR-LSPSVNRFTLYVDLSSNRLK----- 391
            ..:||.:.....:.:.....::.|.||.|..|.:  :.| |....|.|||  |.|.|.|.
plant   631 NFSNNLLTGTIPKELGKLEMVQEIDLSNNLFSGS--IPRSLQACKNVFTL--DFSQNNLSGHIPD 691

  Fly   392 ----------SLNLS-------------SLLHFRYINLADNNWSCNWLVANLVQKLPNSVNFARP 433
                      |||||             ::.|...::|:.||     |...:.:.|.|
plant   692 EVFQGMDMIISLNLSRNSFSGEIPQSFGNMTHLVSLDLSSNN-----LTGEIPESLAN------- 744

  Fly   434 WTVINNLSENTTNVEGIDCIEGGTNRSIILLDVSGVPQPKSDNCDCVVAYDETNPSPPPLTWP-- 496
            .:.:.:|...:.|::| ...|.|..::|...|:.|    .:|.|.          |..||. |
plant   745 LSTLKHLKLASNNLKG-HVPESGVFKNINASDLMG----NTDLCG----------SKKPLK-PCT 793

  Fly   497 -KIPTDRFDSRSVIIWMLVAIAIAF--------------------------------SGLRWLRR 528
             |..:..|..|:.:|.:::..|.|.                                |.|: |:|
plant   794 IKQKSSHFSKRTRVILIILGSAAALLLVLLLVLILTCCKKKEKKIENSSESSLPDLDSALK-LKR 857

  Fly   529 FVDR---------NEKRKLGQKMLHNVYVSKVQ 552
            |..:         |....:|...|..||..:::
plant   858 FEPKELEQATDSFNSANIIGSSSLSTVYKGQLE 890

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380	2/17 (12%)
		LRR_8	64..123	CDD:290566	21/69 (30%)
		leucine-rich repeat	65..88	CDD:275380	7/22 (32%)
		leucine-rich repeat	89..112	CDD:275380	8/22 (36%)
		leucine-rich repeat	113..136	CDD:275380	9/39 (23%)
		LRR_RI	115..384	CDD:238064	95/372 (26%)
		LRR_8	135..195	CDD:290566	19/90 (21%)
		leucine-rich repeat	137..160	CDD:275380	7/46 (15%)
		leucine-rich repeat	161..184	CDD:275380	9/22 (41%)
		LRR_8	184..243	CDD:290566	21/98 (21%)
		leucine-rich repeat	185..208	CDD:275380	7/26 (27%)
		leucine-rich repeat	209..232	CDD:275380	7/22 (32%)
		LRR_8	232..289	CDD:290566	23/85 (27%)
		leucine-rich repeat	233..256	CDD:275380	11/39 (28%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		LRR_8	280..339	CDD:290566	24/61 (39%)
		leucine-rich repeat	281..304	CDD:275380	7/22 (32%)
		leucine-rich repeat	305..328	CDD:275380	12/25 (48%)
FLS2	NP_001330009.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000