DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18095 and GHR1

DIOPT Version :9

Sequence 1:	NP_001188805.1	Gene:	CG18095 / 34823	FlyBaseID:	FBgn0028872	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001320016.1	Gene:	GHR1 / 827842	AraportID:	AT4G20940	Length:	1037	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	140/561 - (24%)
Similarity:	226/561 - (40%)	Gaps:	130/561 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FSPRLSCLQLSKCNNT-------EVTLIRKTELL-TSLTLSNCTLPHVENGFFVRFDHLLHLELQ 71
            ||.....::||..||:       ::...:..:.| .|..|.:.:||. |.|   |...|.:|.|.
plant    74 FSNLTKLVKLSMSNNSLSGVLPNDLGSFKSLQFLDLSDNLFSSSLPK-EIG---RSVSLRNLSLS 134

  Fly    72 HSGLSDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLSKLSVKSFEQYPQ 136
            .:..|.....|:.||..||.|.:|.|:||.....|...|..|..|:||.|..:....:.||....
plant   135 GNNFSGEIPESMGGLISLQSLDMSSNSLSGPLPKSLTRLNDLLYLNLSSNGFTGKMPRGFELISS 199

  Fly   137 LQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGL-HRLSSLSLQHNRIEFIEM 200
            |:.|||..|.|....:..|..|::..::.::||:|....|....|: ..:..|:|.||::|....
plant   200 LEVLDLHGNSIDGNLDGEFFLLTNASYVDISGNRLVTTSGKLLPGVSESIKHLNLSHNQLEGSLT 264

  Fly   201 DSFESNTHLRSLRLDQNLLSS-------------LQFLSQR-------GLAR-----LVHLNLSS 240
            ..|:...:|:.|.|..|:||.             |:..:.|       .|.:     |..|:||.
plant   265 SGFQLFQNLKVLDLSYNMLSGELPGFNYVYDLEVLKLSNNRFSGSLPNNLLKGDSLLLTTLDLSG 329

  Fly   241 NLLQKLEPFVFSKNFELQDLDLSYNNIT-------------KLNKEALSG-------LDSLERLN 285
            |.|......:.|..  |..||||.|::|             .|:.....|       .:::|.|:
plant   330 NNLSGPVSSIMSTT--LHTLDLSSNSLTGELPLLTGGCVLLDLSNNQFEGNLTRWSKWENIEYLD 392

  Fly   286 ISHNYVDKIYDESLDSLIALLQLDISFNLLT-TLPDNLFHFNTQLEEIILANNKIE-----EISS 344
            :|.|:....:.::...|:....|::|:|.|| :||:.:.....:|..:.:::|.:|     .:.|
plant   393 LSQNHFTGSFPDATPQLLRANHLNLSYNKLTGSLPERIPTHYPKLRVLDISSNSLEGPIPGALLS 457

  Fly   345 QMMFNQNHLRYIKLSGNAISDAAFLDRLSPSVNRFTLYVDLSSNR----LKSLNLSSLLHFRYIN 405
            .....:.||:...::||       :..|..|.:|..| :|||.||    |..: ..||.:.:.:|
plant   458 MPTLEEIHLQNNGMTGN-------IGPLPSSGSRIRL-LDLSHNRFDGDLPGV-FGSLTNLQVLN 513

  Fly   406 LADNNWSCNWLVANLVQKLPNSVNFARPWTVINNLSENTTNVEGIDCIEGGTNRSIILLDVS--- 467
            ||.|         ||...||:|:|                     |.:      |:..||||
plant   514 LAAN---------NLSGSLPSSMN---------------------DIV------SLSSLDVSQNH 542

  Fly   468 ---GVPQPKSDNCDCV-VAYDE---TNPS-----PPPLTWP 496
               .:|...|.|.... |:|::   |.|.     |||..:|
plant   543 FTGPLPSNLSSNIMAFNVSYNDLSGTVPENLKNFPPPSFYP 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380	8/23 (35%)
		LRR_8	64..123	CDD:290566	21/58 (36%)
		leucine-rich repeat	65..88	CDD:275380	7/22 (32%)
		leucine-rich repeat	89..112	CDD:275380	9/22 (41%)
		leucine-rich repeat	113..136	CDD:275380	7/22 (32%)
		LRR_RI	115..384	CDD:238064	74/320 (23%)
		LRR_8	135..195	CDD:290566	17/60 (28%)
		leucine-rich repeat	137..160	CDD:275380	8/22 (36%)
		leucine-rich repeat	161..184	CDD:275380	5/23 (22%)
		LRR_8	184..243	CDD:290566	20/83 (24%)
		leucine-rich repeat	185..208	CDD:275380	6/22 (27%)
		leucine-rich repeat	209..232	CDD:275380	9/42 (21%)
		LRR_8	232..289	CDD:290566	19/81 (23%)
		leucine-rich repeat	233..256	CDD:275380	7/22 (32%)
		leucine-rich repeat	257..280	CDD:275380	9/42 (21%)
		LRR_8	280..339	CDD:290566	14/59 (24%)
		leucine-rich repeat	281..304	CDD:275380	5/22 (23%)
		leucine-rich repeat	305..328	CDD:275380	7/23 (30%)
GHR1	NP_001320016.1	PLN00113	2..1036	CDD:215061	140/561 (25%)
		leucine-rich repeat	80..103	CDD:275380	4/22 (18%)
		leucine-rich repeat	104..127	CDD:275380	8/26 (31%)
		leucine-rich repeat	128..151	CDD:275380	7/22 (32%)
		leucine-rich repeat	152..175	CDD:275380	9/22 (41%)
		leucine-rich repeat	176..199	CDD:275380	7/22 (32%)
		leucine-rich repeat	200..223	CDD:275380	8/22 (36%)
		leucine-rich repeat	224..248	CDD:275380	5/23 (22%)
		leucine-rich repeat	249..272	CDD:275380	6/22 (27%)
		leucine-rich repeat	296..314	CDD:275380	2/17 (12%)
		leucine-rich repeat	344..387	CDD:275380	9/42 (21%)
		leucine-rich repeat	388..412	CDD:275380	5/23 (22%)
		leucine-rich repeat	413..436	CDD:275380	7/22 (32%)
		leucine-rich repeat	437..460	CDD:275380	4/22 (18%)
		leucine-rich repeat	461..484	CDD:275380	6/29 (21%)
		leucine-rich repeat	485..508	CDD:275380	9/24 (38%)
		leucine-rich repeat	509..532	CDD:275380	11/58 (19%)
		leucine-rich repeat	533..553	CDD:275380	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000