DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18095 and fmodb

DIOPT Version :9

Sequence 1:	NP_001188805.1	Gene:	CG18095 / 34823	FlyBaseID:	FBgn0028872	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	XP_001338027.1	Gene:	fmodb / 797559	ZFINID:	ZDB-GENE-080327-28	Length:	362	Species:	Danio rerio

Alignment Length:	360	Identity:	94/360 - (26%)
Similarity:	150/360 - (41%)	Gaps:	87/360 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 NGLTKLQYL---------SLSHN-NLSSLRSWSSEP--LGALTNLD------------------- 117
            |.||.|.||         ..||| |.:|||: ..||  |......|
Zfish    23 NSLTWLSYLRNRAYSHGYGRSHNGNYASLRN-EDEPSVLDCPLECDCPPAYPKAMYCNNRKLQHV 86

  Fly   118 -----------LSHNMLSKLSVKSFEQYPQLQQLDLRYNRIS--QIENDSFDGLSHLKHLYLNGN 169
                       |.:|.::.::...|:..|.|..:.:..|:::  :|.:..|..|.:|:.|:|..|
Zfish    87 PFVPSHIKYVYLQNNQITGITNGVFDNAPNLTWIIMHANKLTSDKIGDKVFAKLPNLQRLFLQNN 151

  Fly   170 QLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRLDQNLLSSLQFLSQRGLARLV 234
            .|:.:....   .|.|..|.|.||.|..:.::||...::|.:|.|..|.:..|. .:.:||..|.
Zfish   152 NLSRVPQDL---PHSLRDLHLNHNNISVVPLNSFHGMSNLTALYLQANAIEDLG-NALKGLLSLT 212

  Fly   235 HLNLSSNLL----QKLEPFVFSKNFELQDLDLSYNNITKLNKEALSGLDSLERLNISHNYVD--- 292
            .|:|..|.|    |.|.|       :|..|.|.||.|:.:..:.||....|..:.:|||.:.
Zfish   213 VLDLRGNRLKMIPQSLPP-------KLSQLYLEYNYISSIPADFLSQRPDLRFVRLSHNQLTNGG 270

  Fly   293 ---KIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNTQLEEIILANNKIEEISSQMMF------ 348
               ..::.|     .|::||:|||.|..:|.    .:|.||.:.|..|||:|.|.....
Zfish   271 IPANAFNVS-----TLVELDLSFNKLERIPT----ISTSLENLYLQANKIKEFSVSSFCRVVDTN 326

  Fly   349 NQNHLRYIKLSGNAI------SDAAFLDRLSPSVN 377
            |.::||.::|..|.|      ::|....||:.:::
Zfish   327 NYSNLRVLRLEANEITPRDIPNEAVLCLRLATNID 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380
		LRR_8	64..123	CDD:290566	19/80 (24%)
		leucine-rich repeat	65..88	CDD:275380	2/3 (67%)
		leucine-rich repeat	89..112	CDD:275380	13/34 (38%)
		leucine-rich repeat	113..136	CDD:275380	4/52 (8%)
		LRR_RI	115..384	CDD:238064	78/317 (25%)
		LRR_8	135..195	CDD:290566	17/61 (28%)
		leucine-rich repeat	137..160	CDD:275380	5/24 (21%)
		leucine-rich repeat	161..184	CDD:275380	5/22 (23%)
		LRR_8	184..243	CDD:290566	19/58 (33%)
		leucine-rich repeat	185..208	CDD:275380	8/22 (36%)
		leucine-rich repeat	209..232	CDD:275380	7/22 (32%)
		LRR_8	232..289	CDD:290566	18/60 (30%)
		leucine-rich repeat	233..256	CDD:275380	8/26 (31%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		LRR_8	280..339	CDD:290566	18/64 (28%)
		leucine-rich repeat	281..304	CDD:275380	5/28 (18%)
		leucine-rich repeat	305..328	CDD:275380	8/22 (36%)
fmodb	XP_001338027.1	LRRNT	61..95	CDD:214470	1/33 (3%)
		LRR_8	91..153	CDD:290566	13/61 (21%)
		leucine-rich repeat	94..116	CDD:275380	3/21 (14%)
		leucine-rich repeat	117..142	CDD:275380	5/24 (21%)
		LRR_RI	136..345	CDD:238064	67/228 (29%)
		LRR_8	141..198	CDD:290566	18/59 (31%)
		leucine-rich repeat	143..163	CDD:275380	5/22 (23%)
		leucine-rich repeat	164..187	CDD:275380	8/22 (36%)
		leucine-rich repeat	188..210	CDD:275380	7/22 (32%)
		LRR_8	210..266	CDD:290566	20/62 (32%)
		leucine-rich repeat	211..231	CDD:275380	8/26 (31%)
		leucine-rich repeat	232..255	CDD:275380	8/22 (36%)
		leucine-rich repeat	256..280	CDD:275380	5/28 (18%)
		leucine-rich repeat	281..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..321	CDD:275380	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45712
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010