Protein Alignment CG18095 and Lrg1

DIOPT Version :9

• Sequence 1: NP_001188805.1
• Gene: CG18095 / 34823
• FlyBaseID: FBgn0028872
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_084072.1
• Gene: Lrg1 / 76905
• MGIID: 1924155
• Length: 342
• Species: Mus musculus
• Alignment Length: 310
• Identity: 89/310 - (28%)
• Similarity: 137/310 - (44%)
• Gaps: 68/310 - (21%)

  Fly   188 LSLQHNRIEFIEMDSFESNTHLRSLRLDQNLLSSLQFLSQRGLA---RLVHLNLSSNLLQKLEPF 249
            ||::.:.:..:...:.:....||.|.|..|   .||.||...||   ||..|:|:.|.|:.|.|.
Mouse    66 LSVEFSNLTQLPAAALQGCPGLRELHLSSN---RLQALSPELLAPVPRLRALDLTRNALRSLPPG 127

  Fly   250 VFSKNFELQDLDLSYNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLDSLIALLQLDISFNL 314
            :||.:..|..|.|..|.:.:::.:.|.|||:|..|:::.|.:..:....|.||.||..||:.:||
Mouse   128 LFSTSANLSTLVLRENQLREVSAQWLQGLDALGHLDLAENQLSSLPSGLLASLGALHTLDLGYNL 192

  Fly   315 LTTLPDNLFHFNTQLEEIILANNKIEEISSQMMFNQNHLRYIKLSGNAISDAA--------FLDR 371
            |.:||:.|.....:|:.:.|..|:::.:...::..|..||.:.|:.|.:...|        .||.
Mouse   193 LESLPEGLLRGPRRLQRLHLEGNRLQRLEDSLLAPQPFLRVLFLNDNQLVGVATGSFQGLQHLDM 257

  Fly   372 LSPSVNRFTLYVDLSSNRLKSL--NLSSLL--------------HFRYI---NLADNNWSCNWLV 417
            |           |||:|.|.|.  .|.:.|              |..:|   ||||   .|.|||
Mouse   258 L-----------DLSNNSLSSTPPGLWAFLGRPTRDMQDGFDISHNPWICDKNLAD---LCRWLV 308

  Fly   418 ANLVQKLPNSVNFARPWTVINNLSENTTNVEGIDCIEGGTNRSIILLDVS 467
            ||     .|.:           .|:|.|...|.:.::|..     ||||:
Mouse   309 AN-----RNKM-----------FSQNDTRCAGPEAMKGQR-----LLDVA 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380
		LRR_8	64..123	CDD:290566
		leucine-rich repeat	65..88	CDD:275380
		leucine-rich repeat	89..112	CDD:275380
		leucine-rich repeat	113..136	CDD:275380
		LRR_RI	115..384	CDD:238064	59/206 (29%)
		LRR_8	135..195	CDD:290566	2/6 (33%)
		leucine-rich repeat	137..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380
		LRR_8	184..243	CDD:290566	18/57 (32%)
		leucine-rich repeat	185..208	CDD:275380	2/19 (11%)
		leucine-rich repeat	209..232	CDD:275380	11/25 (44%)
		LRR_8	232..289	CDD:290566	20/56 (36%)
		leucine-rich repeat	233..256	CDD:275380	9/22 (41%)
		leucine-rich repeat	257..280	CDD:275380	7/22 (32%)
		LRR_8	280..339	CDD:290566	19/58 (33%)
		leucine-rich repeat	281..304	CDD:275380	6/22 (27%)
		leucine-rich repeat	305..328	CDD:275380	9/22 (41%)
Lrg1	NP_084072.1	leucine-rich repeat	65..86	CDD:275380	2/19 (11%)
		LRR_8	66..121	CDD:290566	18/57 (32%)
		LRR_RI	<74..294	CDD:238064	66/233 (28%)
		leucine-rich repeat	87..110	CDD:275380	11/25 (44%)
		LRR_8	109..169	CDD:290566	21/59 (36%)
		leucine-rich repeat	111..134	CDD:275380	9/22 (41%)
		leucine-rich repeat	135..158	CDD:275380	7/22 (32%)
		leucine-rich repeat	159..182	CDD:275380	6/22 (27%)
		LRR_8	162..217	CDD:290566	18/54 (33%)
		leucine-rich repeat	183..206	CDD:275380	9/22 (41%)
		LRR_8	205..265	CDD:290566	16/70 (23%)
		leucine-rich repeat	207..230	CDD:275380	4/22 (18%)
		leucine-rich repeat	231..254	CDD:275380	5/22 (23%)
		leucine-rich repeat	255..278	CDD:275380	11/33 (33%)
		LRRCT	292..338	CDD:214507	21/70 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831228
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930