Protein Alignment CG18095 and Lrrtm1

DIOPT Version :10

• Sequence 1: NP_001188805.1
• Gene: CG18095 / 34823
• FlyBaseID: FBgn0028872
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_083156.2
• Gene: Lrrtm1 / 74342
• MGIID: 2389173
• Length: 522
• Species: Mus musculus
• Alignment Length: 489
• Identity: 124/489 - (25%)
• Similarity: 192/489 - (39%)
• Gaps: 104/489 - (21%)

  Fly   112 ALTNLDLSHNMLSKLSVKSFEQYPQLQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDG 176
            ||...:..||:...|.            |.||||.:|::....|.||..|..|||:.|.:..:.|
Mouse    54 ALNLTEAPHNLSGLLG------------LSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQG 106

  Fly   177 SFFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRLDQNLLSSLQFLSQRGLARLVHLNLSSN 241
            ..|:.|.|:..|:|..|:|..:...:|....:|||:.|..|.|.:|......||.:|..|::.:|
Mouse   107 DAFQKLRRVKELTLSSNQITELANTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRAN 171

  Fly   242 LLQKLEPFVFSKNFELQDLDLSYNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLDSLIALL 306
            .:|.:...:|.....|:.||:.||.:..|.:.:.:||..|..|::.||.:.|:
Mouse   172 AIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLIKV------------ 224

  Fly   307 QLDISFNLLTTLPDNLFHFN--TQLEEIILANNKIEEISSQMMFNQNHLRYIKLSGNAISDAAFL 369
                          |..||.  ..|..:.|..||:..:.|.:.:..| |..:.||||.|
Mouse   225 --------------NFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWN-LEKMDLSGNEI------ 268

  Fly   370 DRLSPSVNRFTLY---VDLSSNRLKSLN---LSSLLHFRYINLADNNWSC--------NWLVANL 420
            :.:.|.|.....|   :.|.||||..:.   |:|......|.||.|.|.|        :|| :|.
Mouse   269 EYMEPHVFETVPYLQTLQLDSNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWL-SNF 332

  Fly   421 VQKLPNSVNFARPWTVINNLSENTTNVEGID-------CIEGGTNRSIILLDV-----SGVPQPK 473
            ..:...::..|.|        |.....:.:|       |.:|....|..||.|     |.:..|:
Mouse   333 QGRYDANLQCASP--------EYAQGEDVLDAVYAFHLCEDGAEPTSGHLLSVAVTNRSDLTPPE 389

  Fly   474 SDNCDCVVAYDETNPSPPPLTWPKIPTDRFDSRSVIIWMLV--AIAIAFS--------------- 521
            |.....|...:..:.:..|:| ..:|.......:|.|..:|  .:|:.||
Mouse   390 SSATTLVDGGEGHDGTFEPIT-VALPGGEHAENAVQIHKVVTGTMALIFSFLIVVLVLYVSWKCF 453

  Fly   522 --GLRWLRR-FVDRNEKRKLGQKMLHNVYVSKVQ 552
              .||.||: ||.:..|:|..|.| |.:.....|
Mouse   454 PASLRQLRQCFVTQRRKQKQKQTM-HQMAAMSAQ 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	LRR	22..>338	CDD:443914	60/227 (26%)
		leucine-rich repeat	41..64	CDD:275380
		leucine-rich repeat	65..88	CDD:275380
		leucine-rich repeat	89..112	CDD:275380	124/489 (25%)
		leucine-rich repeat	113..136	CDD:275380	4/22 (18%)
		leucine-rich repeat	137..160	CDD:275380	9/22 (41%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..208	CDD:275380	5/22 (23%)
		leucine-rich repeat	209..232	CDD:275380	9/22 (41%)
		leucine-rich repeat	233..256	CDD:275380	5/22 (23%)
		leucine-rich repeat	257..280	CDD:275380	8/22 (36%)
		leucine-rich repeat	281..304	CDD:275380	5/22 (23%)
		leucine-rich repeat	305..328	CDD:275380	3/24 (13%)
Lrrtm1	NP_083156.2	LRR	49..>315	CDD:443914	83/305 (27%)
		LRR 1	64..87		8/34 (24%)
		LRR 2	89..111		7/21 (33%)
		leucine-rich repeat	91..114	CDD:275380	8/22 (36%)
		LRR 3	112..135		7/22 (32%)
		leucine-rich repeat	115..138	CDD:275380	5/22 (23%)
		LRR 4	136..159		7/22 (32%)
		leucine-rich repeat	139..162	CDD:275380	9/22 (41%)
		LRR 5	161..183		5/21 (24%)
		leucine-rich repeat	163..186	CDD:275380	5/22 (23%)
		LRR 6	184..207		6/22 (27%)
		leucine-rich repeat	187..210	CDD:275380	8/22 (36%)
		LRR 7	209..231		8/47 (17%)
		leucine-rich repeat	211..234	CDD:275380	8/48 (17%)
		LRR 8	233..255		5/21 (24%)
		leucine-rich repeat	235..257	CDD:275380	5/21 (24%)
		LRR 9	256..278		9/28 (32%)
		leucine-rich repeat	258..281	CDD:275380	8/28 (29%)
		LRR 10	280..302		7/21 (33%)
		leucine-rich repeat	282..300	CDD:275380	5/17 (29%)
		leucine-rich repeat	306..318	CDD:275378	5/11 (45%)