DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18095 and Aspn

DIOPT Version :9

Sequence 1:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_001165952.1 Gene:Aspn / 66695 MGIID:1913945 Length:373 Species:Mus musculus


Alignment Length:263 Identity:72/263 - (27%)
Similarity:128/263 - (48%) Gaps:21/263 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 QQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDS 202
            :.:||:.|:|.:|:.:.|.||:.|..|.||.|:|..|....|....:|..|.|.||::..|.::.
Mouse    98 RMVDLQNNKIKEIKENDFKGLTSLYALILNNNKLTKIHPKTFLTTKKLRRLYLSHNQLSEIPLNL 162

  Fly   203 FESNTHLRSLRLDQNLLSSLQFLSQRGLARLVHLNLSSNLLQK--LEPFVFS--KNFELQDLDLS 263
            .:|   |..||:..|.:..:|..:.:|:..|..|.:|:|.|:.  :||..|.  ..|.::..:..
Mouse   163 PKS---LAELRIHDNKVKKIQKDTFKGMNALHVLEMSANPLENNGIEPGAFEGVTVFHIRIAEAK 224

  Fly   264 YNNITKLNKEALSGL-DSLERLNISHNYVDKIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNT 327
            ..:|.|       || .:|..|::..|.:..:..|.|.....|.:|.:..|.:|.:.:..|....
Mouse   225 LTSIPK-------GLPPTLLELHLDFNKISTVELEDLKRYRELQRLGLGNNRITDIENGTFANIP 282

  Fly   328 QLEEIILANNKIEEISSQMMFNQNHLRYIKLSGNAISDAAFLDRLSPSVNRF--TLY--VDLSSN 388
            ::.||.|.:||:::|.|.:. ...:|:.|.|..|:|:.....| ..|:|.:.  :||  :.|.:|
Mouse   283 RVREIHLEHNKLKKIPSGLQ-ELKYLQIIFLHYNSIAKVGVND-FCPTVPKMKKSLYSAISLFNN 345

  Fly   389 RLK 391
            .:|
Mouse   346 PMK 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380
LRR_8 64..123 CDD:290566
leucine-rich repeat 65..88 CDD:275380
leucine-rich repeat 89..112 CDD:275380
leucine-rich repeat 113..136 CDD:275380
LRR_RI 115..384 CDD:238064 69/254 (27%)
LRR_8 135..195 CDD:290566 21/56 (38%)
leucine-rich repeat 137..160 CDD:275380 8/21 (38%)
leucine-rich repeat 161..184 CDD:275380 8/22 (36%)
LRR_8 184..243 CDD:290566 17/58 (29%)
leucine-rich repeat 185..208 CDD:275380 7/22 (32%)
leucine-rich repeat 209..232 CDD:275380 6/22 (27%)
LRR_8 232..289 CDD:290566 15/61 (25%)
leucine-rich repeat 233..256 CDD:275380 8/26 (31%)
leucine-rich repeat 257..280 CDD:275380 4/23 (17%)
LRR_8 280..339 CDD:290566 14/58 (24%)
leucine-rich repeat 281..304 CDD:275380 5/22 (23%)
leucine-rich repeat 305..328 CDD:275380 5/22 (23%)
AspnNP_001165952.1 LRRNT 68..97 CDD:214470
leucine-rich repeat 77..96 CDD:275380
LRR 1 96..117 6/18 (33%)
leucine-rich repeat 97..120 CDD:275380 8/21 (38%)
LRR_8 98..155 CDD:290566 21/56 (38%)
LRR 2 120..141 8/20 (40%)
leucine-rich repeat 121..144 CDD:275380 8/22 (36%)
LRR_RI <139..333 CDD:238064 52/205 (25%)
LRR 3 144..166 7/24 (29%)
leucine-rich repeat 145..165 CDD:275380 6/19 (32%)
Interaction with TGFB1 159..205 12/48 (25%)
leucine-rich repeat 166..189 CDD:275380 6/22 (27%)
LRR 5 189..212 8/22 (36%)
leucine-rich repeat 190..215 CDD:275380 8/24 (33%)
LRR_8 234..294 CDD:290566 14/59 (24%)
LRR 6 235..255 4/19 (21%)
leucine-rich repeat 236..259 CDD:275380 5/22 (23%)
LRR 7 259..280 5/20 (25%)
leucine-rich repeat 260..283 CDD:275380 5/22 (23%)
LRR 8 283..305 7/22 (32%)
LRR 9 306..327 6/21 (29%)
leucine-rich repeat 307..331 CDD:275380 8/24 (33%)
LRR 10 328..349 6/21 (29%)
leucine-rich repeat 332..359 CDD:275380 5/17 (29%)
LRR 11 350..373
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45712
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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