DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18095 and dcn

DIOPT Version :9

Sequence 1:	NP_001188805.1	Gene:	CG18095 / 34823	FlyBaseID:	FBgn0028872	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_571772.1	Gene:	dcn / 64698	ZFINID:	ZDB-GENE-010102-1	Length:	373	Species:	Danio rerio

Alignment Length:	371	Identity:	91/371 - (24%)
Similarity:	155/371 - (41%)	Gaps:	70/371 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KTELLTSLTLSNC-TLPHVENGF--FVRFD------------------HLLHLELQ--------- 71
            |:..|:.|.:|.| .||..::||  ||..|                  |:..|.:.
Zfish     2 KSACLSLLLVSVCWALPFRQSGFMDFVMEDEPASGDGPGPELPTTRKPHVERLPMMPEGPEVPFC 66

  Fly    72 ------HSGLSDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLSKLSVKS 130
                  |..::...|..|..:.:                  ..||.. |.|||.:|.::::....
Zfish    67 PFRCQCHLRVAQCSDLGLKTVPE------------------KIPLDT-TLLDLQNNKITEIKEND 112

  Fly   131 FEQYPQLQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRI 195
            |:....||.|.|..|:|:.|...:|..|.:|:.|||:.|.|..:..:..:.   |..|.:..|:|
Zfish   113 FKGLKGLQTLILVNNKITIIHAKAFSSLINLERLYLSKNLLKEVPANIPKS---LQELRIHENQI 174

  Fly   196 EFIEMDSFESNTHLRSLRLDQNLLSS--LQFLSQRGLARLVHLNLSSNLLQKLEPFVFSKNFELQ 258
            ..|:..||....::..:.|..|.|||  :...:...|.|:.::.::...|..:...:.|..|||.
Zfish   175 NKIKKSSFAGMANVIVMELGSNPLSSSGVDNGAFADLKRVSYIRIADTNLTSIPKGLPSSLFELH 239

  Fly   259 DLDLSYNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLDSLIALLQLDISFNLLTTLPDNLF 323
               |..|.|||:..::|.||.:|.:|.:|||.:..:.:.||.::..|.:|.:..|.||.:|..|.
Zfish   240 ---LDGNKITKVTADSLKGLKNLSKLGLSHNEISVVENGSLANVPHLRELHLENNALTAVPAGLA 301

  Fly   324 HFNTQLEEIILANNKIEEISSQMM----FNQNHLRY--IKLSGNAI 363
            . :..::.|.|.:|||..:.::..    :|.....|  |.|..|.:
Zfish   302 D-HKYIQVIYLHSNKIAAVGTEDFCPPGYNTKKAMYSGISLFSNPV 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380	11/43 (26%)
		LRR_8	64..123	CDD:290566	12/73 (16%)
		leucine-rich repeat	65..88	CDD:275380	4/37 (11%)
		leucine-rich repeat	89..112	CDD:275380	2/22 (9%)
		leucine-rich repeat	113..136	CDD:275380	6/22 (27%)
		LRR_RI	115..384	CDD:238064	71/257 (28%)
		LRR_8	135..195	CDD:290566	18/59 (31%)
		leucine-rich repeat	137..160	CDD:275380	9/22 (41%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		LRR_8	184..243	CDD:290566	14/60 (23%)
		leucine-rich repeat	185..208	CDD:275380	7/22 (32%)
		leucine-rich repeat	209..232	CDD:275380	6/24 (25%)
		LRR_8	232..289	CDD:290566	17/56 (30%)
		leucine-rich repeat	233..256	CDD:275380	2/22 (9%)
		leucine-rich repeat	257..280	CDD:275380	9/22 (41%)
		LRR_8	280..339	CDD:290566	17/58 (29%)
		leucine-rich repeat	281..304	CDD:275380	7/22 (32%)
		leucine-rich repeat	305..328	CDD:275380	7/22 (32%)
dcn	NP_571772.1	LRRNT	66..97	CDD:214470	5/49 (10%)
		LRR_RI	<70..174	CDD:238064	29/125 (23%)
		leucine-rich repeat	74..94	CDD:275380	3/37 (8%)
		leucine-rich repeat	95..118	CDD:275380	6/23 (26%)
		LRR_8	96..153	CDD:290566	20/56 (36%)
		leucine-rich repeat	119..142	CDD:275380	9/22 (41%)
		leucine-rich repeat	143..163	CDD:275380	6/19 (32%)
		LRR_8	162..224	CDD:290566	14/64 (22%)
		leucine-rich repeat	164..187	CDD:275380	7/22 (32%)
		leucine-rich repeat	188..213	CDD:275380	6/24 (25%)
		leucine-rich repeat	214..234	CDD:275380	1/19 (5%)
		LRR_RI	<233..>326	CDD:238064	31/96 (32%)
		LRR_8	233..293	CDD:290566	22/62 (35%)
		leucine-rich repeat	235..258	CDD:275380	11/25 (44%)
		leucine-rich repeat	259..282	CDD:275380	7/22 (32%)
		leucine-rich repeat	306..325	CDD:275380	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45712
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100