DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18095 and PRELP

DIOPT Version :9

Sequence 1:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_002716.1 Gene:PRELP / 5549 HGNCID:9357 Length:382 Species:Homo sapiens


Alignment Length:287 Identity:85/287 - (29%)
Similarity:131/287 - (45%) Gaps:39/287 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 LDLSHNMLSKLSVKSFEQYPQLQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGSFFR 180
            |.|.:|.:::|.|:||:....|:.::|..|||.:|:....:.|..|..||:..|||..:..:..|
Human   107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPR 171

  Fly   181 GLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRLDQNLLSSLQFLSQ--RGLARLVHLNLSSNLL 243
            .|.:   |.|..|.|..|....|....:|..|.|..|.||...|...  .||..|:.|||:.|:|
Human   172 NLEQ---LRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNIL 233

  Fly   244 QKLEPFVFSKNFELQDLDLSYNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLD----SLIA 304
            :|:.|.|.:   .:..|.|..|.|..:.........:|..:.:::|   |:.|..|.    ::..
Human   234 RKMPPRVPT---AIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYN---KLTDRGLPKNSFNISN 292

  Fly   305 LLQLDISFNLLTTLPDNLFHFNTQLEEIILANNKIEEIS---------------SQMMFNQNHLR 354
            ||.|.:|.|.::::|    ..|.:||.:.|.||.||:|:               |..:.|..|||
Human   293 LLVLHLSHNRISSVP----AINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLR 353

  Fly   355 YIKLSGNAISDAAFLD-----RLSPSV 376
            |::|.||.:.....||     ||..||
Human   354 YLRLDGNYLKPPIPLDLMMCFRLLQSV 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380
LRR_8 64..123 CDD:290566 3/6 (50%)
leucine-rich repeat 65..88 CDD:275380
leucine-rich repeat 89..112 CDD:275380
leucine-rich repeat 113..136 CDD:275380 7/19 (37%)
LRR_RI 115..384 CDD:238064 85/287 (30%)
LRR_8 135..195 CDD:290566 18/59 (31%)
leucine-rich repeat 137..160 CDD:275380 7/22 (32%)
leucine-rich repeat 161..184 CDD:275380 8/22 (36%)
LRR_8 184..243 CDD:290566 20/60 (33%)
leucine-rich repeat 185..208 CDD:275380 6/22 (27%)
leucine-rich repeat 209..232 CDD:275380 9/24 (38%)
LRR_8 232..289 CDD:290566 14/56 (25%)
leucine-rich repeat 233..256 CDD:275380 9/22 (41%)
leucine-rich repeat 257..280 CDD:275380 4/22 (18%)
LRR_8 280..339 CDD:290566 17/62 (27%)
leucine-rich repeat 281..304 CDD:275380 5/26 (19%)
leucine-rich repeat 305..328 CDD:275380 7/22 (32%)
PRELPNP_002716.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 19..66
LRRNT 72..107 CDD:214470 85/287 (30%)
LRR 1 95..114 3/6 (50%)
LRR_8 102..162 CDD:316378 18/54 (33%)
leucine-rich repeat 104..127 CDD:275380 7/19 (37%)
LRR 2 115..138 7/22 (32%)
leucine-rich repeat 128..151 CDD:275380 7/22 (32%)
NEL <133..>353 CDD:330839 65/232 (28%)
LRR 3 139..162 6/22 (27%)
leucine-rich repeat 152..172 CDD:275380 6/19 (32%)
LRR 4 163..183 5/22 (23%)
leucine-rich repeat 173..196 CDD:275380 7/25 (28%)
LRR 5 184..207 6/22 (27%)
leucine-rich repeat 197..222 CDD:275380 9/24 (38%)
LRR 6 208..233 9/24 (38%)
leucine-rich repeat 223..243 CDD:275380 9/22 (41%)
LRR 7 234..254 6/22 (27%)
leucine-rich repeat 244..267 CDD:275380 4/22 (18%)
LRR 8 255..278 2/25 (8%)
leucine-rich repeat 268..292 CDD:275380 5/26 (19%)
LRR 9 279..303 7/23 (30%)
LRR 10 304..323 7/22 (32%)
LRR 11 324..362 11/37 (30%)
LRR 12 363..382 6/18 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45712
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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