Protein Alignment CG18095 and Flrt2

DIOPT Version :10

• Sequence 1: NP_001188805.1
• Gene: CG18095 / 34823
• FlyBaseID: FBgn0028872
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_958926.1
• Gene: Flrt2 / 399558
• MGIID: 3603594
• Length: 660
• Species: Mus musculus
• Alignment Length: 455
• Identity: 100/455 - (21%)
• Similarity: 181/455 - (39%)
• Gaps: 119/455 - (26%)

  Fly   164 LYLNGNQLAHIDGSFFRGLHRLSSLS---LQHNRIEFIEMDSFESN--THLRSLRLDQNLLSSLQ 223
            |||:.||:.  :..|...||.:.|:.   |..|     ::|.|..|  .::|.|.|.:|   ::|
Mouse    68 LYLHNNQIN--NAGFPAELHNVQSVHTVYLYGN-----QLDEFPMNLPKNVRVLHLQEN---NIQ 122

  Fly   224 FLSQRGLARLV---HLNLSSNLLQK--LEPFVFSKNFELQDLDLSYNNITKLNKEALSGLD-SLE 282
            .:|:..||:|:   .|:|..|.:..  :|...|.:...|:.|.||.|:::.:.    .||. .|:
Mouse   123 TISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVP----VGLPVDLQ 183

  Fly   283 RLNISHNYVDKIYDESLDSLIALLQLDISFNLLTT--LPDNLFHFNTQLEEIILANNKIEEISS- 344
            .|.:..|.:..|.|.:..:|.:|.:|.:..||||.  :.:..|...|:|:|..:..|.:.....
Mouse   184 ELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPD 248

  Fly   345 -------QMMFNQNHLRYIKLSGNAISDAAFLDRLSPSVNRFTLYVDLSSNRLKSLN---LSSLL 399
                   ::....|.:.:|.|:  |.::...|:||           |:|:|:|:.|.   ...|.
Mouse   249 LPGTHLIRLYLQDNQINHIPLT--AFANLRKLERL-----------DISNNQLRMLTQGVFDHLS 300

  Fly   400 HFRYINLADNNWSCN----WLVANLVQKLPNSVNF----------ARPWTV--IN-NLSENTTNV 447
            :.:.:...:|.|.|:    | |...::.:|:|:|.          .|...|  :| ||....|..
Mouse   301 NLKQLTARNNPWFCDCSIKW-VTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTT 364

  Fly   448 EGIDCIE------GGTNRSIILLDVSGVPQPKSDNCDCVVAYDETNPSPPPLTWPKIP------- 499
            .|:....      ..|.:|..|    .||.|...:         ..|:|.|...|.||
Mouse   365 PGLPVFTPAPSTVSPTTQSPTL----SVPSPSRGS---------VPPAPTPSKLPTIPDWDGRER 416

  Fly   500 -----TDRF--------DSRSVIIWMLVAIAIAFSGLRWLRRFVDRNEKRKLGQKMLHNVYVSKV 551
                 ::|.        |:...:.|:.:...:|:. |.|:          |:|..::..:...::
Mouse   417 VTPPISERIQLSIHFVNDTSIQVSWLSLFTVMAYK-LTWV----------KMGHSLVGGIVQERI 470

  Fly   552  551
            Mouse   471  470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	LRR	22..>338	CDD:443914	51/186 (27%)
		leucine-rich repeat	41..64	CDD:275380
		leucine-rich repeat	65..88	CDD:275380
		leucine-rich repeat	89..112	CDD:275380
		leucine-rich repeat	113..136	CDD:275380
		leucine-rich repeat	137..160	CDD:275380
		leucine-rich repeat	161..184	CDD:275380	7/19 (37%)
		leucine-rich repeat	185..208	CDD:275380	6/27 (22%)
		leucine-rich repeat	209..232	CDD:275380	7/22 (32%)
		leucine-rich repeat	233..256	CDD:275380	6/27 (22%)
		leucine-rich repeat	257..280	CDD:275380	7/23 (30%)
		leucine-rich repeat	281..304	CDD:275380	6/22 (27%)
		leucine-rich repeat	305..328	CDD:275380	7/24 (29%)
Flrt2	NP_958926.1	LRRNT	35..62	CDD:396168
		LRR	50..>310	CDD:443914	65/268 (24%)
		LRR 1. /evidence=ECO:0000255	62..87		8/20 (40%)
		leucine-rich repeat	65..86	CDD:275378	7/19 (37%)
		LRR 2. /evidence=ECO:0000255	88..108		6/24 (25%)
		leucine-rich repeat	90..110	CDD:275380	5/24 (21%)
		LRR 3. /evidence=ECO:0000255	109..131		7/24 (29%)
		leucine-rich repeat	111..134	CDD:275380	9/25 (36%)
		LRR 4. /evidence=ECO:0000255	132..157		6/24 (25%)
		leucine-rich repeat	135..160	CDD:275380	5/24 (21%)
		LRR 5. /evidence=ECO:0000255	159..181		7/25 (28%)
		leucine-rich repeat	161..181	CDD:275380	7/23 (30%)
		leucine-rich repeat	182..205	CDD:275380	6/22 (27%)
		LRR 6. /evidence=ECO:0000255	183..202		4/18 (22%)
		LRR 7. /evidence=ECO:0000255	203..228		8/24 (33%)
		leucine-rich repeat	206..231	CDD:275380	7/24 (29%)
		LRR 8. /evidence=ECO:0000255	229..251		4/21 (19%)
		leucine-rich repeat	232..253	CDD:275380	3/20 (15%)
		LRR 9. /evidence=ECO:0000255	252..274		4/23 (17%)
		leucine-rich repeat	254..277	CDD:275380	4/24 (17%)
		LRR 10. /evidence=ECO:0000255	275..298		8/33 (24%)
		leucine-rich repeat	278..301	CDD:275380	9/33 (27%)
		PCC	282..>359	CDD:188093	19/77 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..413		12/54 (22%)
		fn3	426..494	CDD:394996	7/56 (13%)