DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18095 and LRRC26

DIOPT Version :9

Sequence 1:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_001013675.1 Gene:LRRC26 / 389816 HGNCID:31409 Length:334 Species:Homo sapiens


Alignment Length:196 Identity:62/196 - (31%)
Similarity:90/196 - (45%) Gaps:10/196 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 PGSLLLLIFSFSPRLSCLQLSKCNNTEVTLIRK--TELLTSLT--LSNC---TLPHVENGFFVRF 62
            |..||||:...||.....|:|...:...:|...  .|:.|.:.  |::|   :||.|..|..:|.
Human     9 PRPLLLLLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVPGGLASCSALSLPAVPPGLSLRL 73

  Fly    63 DHLLHLELQHSGLSDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLSKLS 127
            ..||   |.|:.:..|...:..|...||.|.|..|.|.|:...:...||||..||||.|.|..|:
Human    74 RALL---LDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALA 135

  Fly   128 VKSFEQYPQLQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQH 192
            ..:|.....|:.|.|..||::::|..:...|..|:.|.|..|:||.:.......|..|.:|.|:.
Human   136 PGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRG 200

  Fly   193 N 193
            |
Human   201 N 201

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380 8/27 (30%)
LRR_8 64..123 CDD:290566 22/58 (38%)
leucine-rich repeat 65..88 CDD:275380 6/22 (27%)
leucine-rich repeat 89..112 CDD:275380 8/22 (36%)
leucine-rich repeat 113..136 CDD:275380 9/22 (41%)
LRR_RI 115..384 CDD:238064 26/79 (33%)
LRR_8 135..195 CDD:290566 18/59 (31%)
leucine-rich repeat 137..160 CDD:275380 7/22 (32%)
leucine-rich repeat 161..184 CDD:275380 7/22 (32%)
LRR_8 184..243 CDD:290566 4/10 (40%)
leucine-rich repeat 185..208 CDD:275380 4/9 (44%)
leucine-rich repeat 209..232 CDD:275380
LRR_8 232..289 CDD:290566
leucine-rich repeat 233..256 CDD:275380
leucine-rich repeat 257..280 CDD:275380
LRR_8 280..339 CDD:290566
leucine-rich repeat 281..304 CDD:275380
leucine-rich repeat 305..328 CDD:275380
LRRC26NP_001013675.1 LRR 1 72..93 6/23 (26%)
LRR 2 96..117 7/20 (35%)
LRR_RI 97..>253 CDD:238064 37/105 (35%)
LRR_8 97..155 CDD:290566 23/57 (40%)
leucine-rich repeat 97..120 CDD:275380 8/22 (36%)
LRR 3 120..141 10/20 (50%)
leucine-rich repeat 121..144 CDD:275380 9/22 (41%)
LRR_8 143..202 CDD:290566 18/59 (31%)
LRR 4 144..167 6/22 (27%)
leucine-rich repeat 145..168 CDD:275380 7/22 (32%)
LRR 5 168..190 6/21 (29%)
leucine-rich repeat 169..192 CDD:275380 7/22 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 298..334
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141283
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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