DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG18095 and Tril

DIOPT Version :9

Sequence 1:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_001029182.1 Gene:Tril / 362364 RGDID:1310827 Length:811 Species:Rattus norvegicus


Alignment Length:460 Identity:124/460 - (26%)
Similarity:197/460 - (42%) Gaps:56/460 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 SFSPRLSCL----------QLSKCNNTEVTLIRKTELLTSLTLSNCTLPHVENGFFVRFDHLLHL 68
            :|.||...:          |...|.|..:..:.||.          :||..::        :|..
  Rat    18 AFPPRAESVCPERCDCQHPQHLLCTNRGLRAVPKTS----------SLPSPQD--------VLTY 64

  Fly    69 ELQHSGLSDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLSKLSVKSFEQ 133
            .|..:.::::..|..:.|.:|:.|.|.:|.:.||...:.|.|..|..|.|.:|:|..|:..:...
  Rat    65 SLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAP 129

  Fly   134 YPQLQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFI 198
            ..:|:.|....|.|.::...||:||..|..|.|:||.|..:..:.|..|..|..|.|:.|||.|:
  Rat   130 LRKLRILYANGNEIGRLSRGSFEGLESLVKLRLDGNVLGALPDAVFAPLGNLLYLHLEANRIRFL 194

  Fly   199 EMDSFESNTHLRSLRLDQN-LLSSLQ----FLSQRGLARLVHLNLSSNLLQKLEPFVFSKNFELQ 258
            ..::|.....||.|.|..| |..||:    |:..|.|:.|:   ||:|.||.|.|.||.....|.
  Rat   195 GKNAFTQLGKLRFLNLSANELQPSLRHAATFVPLRSLSTLI---LSANSLQHLGPRVFQHLPRLG 256

  Fly   259 DLDLSYNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLDSLIALLQLDISFNLLTTLPDNLF 323
            .|.||.|.:|.|..||..||::|..|.:..|.::::....|:.|.:|..||:|.|.|:.|....|
  Rat   257 LLSLSGNQLTHLAPEAFWGLEALRELRLEGNRLNQLPLTLLEPLHSLEALDLSGNELSALHPATF 321

  Fly   324 HFNTQLEEIILANNKIEEISSQMMFNQNHLRYIKLSGNAISDAAFLDRLSPSVNRFTLYVDLSSN 388
            ....:|.|:.|.:|.:..:|..:......|..:.|.||..:....|..|...:..:.     |..
  Rat   322 GHQGRLRELSLRDNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRWMGNWH-----SQG 381

  Fly   389 RLKSLNLS----SLLHFRYINLADN----NWSCNWLVANLVQKLPNSVNFARPWTVINNLSENTT 445
            ||.::.:.    ..|..:|::..|:    |.||       |...|:....:|.|.:.....|..|
  Rat   382 RLLTVFVQCRHPPALRGKYLDYLDDQLLQNGSC-------VDPSPSPTAGSRQWPISTAPGEGMT 439

  Fly   446 NVEGI 450
            ...|:
  Rat   440 PPAGL 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380 2/22 (9%)
LRR_8 64..123 CDD:290566 16/58 (28%)
leucine-rich repeat 65..88 CDD:275380 4/22 (18%)
leucine-rich repeat 89..112 CDD:275380 8/22 (36%)
leucine-rich repeat 113..136 CDD:275380 6/22 (27%)
LRR_RI 115..384 CDD:238064 85/273 (31%)
LRR_8 135..195 CDD:290566 20/59 (34%)
leucine-rich repeat 137..160 CDD:275380 8/22 (36%)
leucine-rich repeat 161..184 CDD:275380 8/22 (36%)
LRR_8 184..243 CDD:290566 23/63 (37%)
leucine-rich repeat 185..208 CDD:275380 8/22 (36%)
leucine-rich repeat 209..232 CDD:275380 11/27 (41%)
LRR_8 232..289 CDD:290566 23/56 (41%)
leucine-rich repeat 233..256 CDD:275380 10/22 (45%)
leucine-rich repeat 257..280 CDD:275380 11/22 (50%)
LRR_8 280..339 CDD:290566 17/58 (29%)
leucine-rich repeat 281..304 CDD:275380 5/22 (23%)
leucine-rich repeat 305..328 CDD:275380 8/22 (36%)
TrilNP_001029182.1 LRR_RI 22..313 CDD:238064 92/311 (30%)
leucine-rich repeat 37..57 CDD:275378 6/29 (21%)
LRR 1 61..81 3/19 (16%)
LRR_8 84..143 CDD:290566 17/58 (29%)
LRR 2 84..105 6/20 (30%)
leucine-rich repeat 85..108 CDD:275380 8/22 (36%)
LRR 3 108..129 6/20 (30%)
leucine-rich repeat 109..132 CDD:275380 6/22 (27%)
LRR 4 132..153 6/20 (30%)
leucine-rich repeat 133..156 CDD:275380 8/22 (36%)
LRR_8 156..215 CDD:290566 21/58 (36%)
LRR 5 156..177 7/20 (35%)
leucine-rich repeat 157..180 CDD:275380 8/22 (36%)
LRR 6 180..201 8/20 (40%)
leucine-rich repeat 181..204 CDD:275380 8/22 (36%)
LRR 7 204..223 8/18 (44%)
leucine-rich repeat 205..230 CDD:275380 9/24 (38%)
LRR_8 229..289 CDD:290566 26/62 (42%)
LRR 8 230..251 11/23 (48%)
leucine-rich repeat 231..254 CDD:275380 11/25 (44%)
LRR 9 254..275 9/20 (45%)
leucine-rich repeat 255..278 CDD:275380 11/22 (50%)
LRR 10 278..298 3/19 (16%)
leucine-rich repeat 279..302 CDD:275380 5/22 (23%)
LRR_8 302..359 CDD:290566 15/56 (27%)
LRR 11 302..323 8/20 (40%)
leucine-rich repeat 303..323 CDD:275380 8/19 (42%)
LRR 12 326..347 5/20 (25%)
leucine-rich repeat 327..340 CDD:275378 4/12 (33%)
leucine-rich repeat 351..363 CDD:275378 4/11 (36%)
TPKR_C2 359..406 CDD:301599 8/51 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 414..460 8/38 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 486..562
FN3 589..661 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166334957
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.840

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