DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18095 and Lgi4

DIOPT Version :9

Sequence 1:	NP_001188805.1	Gene:	CG18095 / 34823	FlyBaseID:	FBgn0028872	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_955793.1	Gene:	Lgi4 / 361549	RGDID:	735035	Length:	537	Species:	Rattus norvegicus

Alignment Length:	181	Identity:	51/181 - (28%)
Similarity:	85/181 - (46%)	Gaps:	28/181 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LTNLDLSHNMLSKLSVKSFEQYPQLQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGS 177
            |.:|.|....:|:|...||.:.|.|..|....|..|.||.|:|.|||:|::|::..|::..|..:
  Rat    54 LLSLSLVRMGVSRLKAGSFLKMPSLHLLLFTSNTFSVIEGDAFIGLSYLQYLFIEDNKIGSISKN 118

  Fly   178 FFRGLHRLSSLSLQHNRIEFIE---MDSFESNTHL----RSLRLDQNLLSSLQFLSQ-------- 227
            ..|||..|:.|||.:|.:|.:.   ....|:.||:    ...:.|..:|..||::..
  Rat   119 ALRGLRSLTHLSLANNHLEALPRFLFQGLETLTHVDLRGNPFQCDCRVLWLLQWMPMVNASVGTG 183

  Fly   228 --RGLARLVHLNLSSNLLQKLEPFVFSKNFELQDLDLSYNNITKLNKEALS 276
              .|.:.|..:.|:     .|:|    |.|:.:..:||:  :..:.:.|||
  Rat   184 ACAGPSALAQIQLN-----HLDP----KKFKCKATELSW--LQTVGESALS 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380
		LRR_8	64..123	CDD:290566	3/9 (33%)
		leucine-rich repeat	65..88	CDD:275380
		leucine-rich repeat	89..112	CDD:275380
		leucine-rich repeat	113..136	CDD:275380	7/22 (32%)
		LRR_RI	115..384	CDD:238064	50/179 (28%)
		LRR_8	135..195	CDD:290566	24/59 (41%)
		leucine-rich repeat	137..160	CDD:275380	10/22 (45%)
		leucine-rich repeat	161..184	CDD:275380	7/22 (32%)
		LRR_8	184..243	CDD:290566	16/75 (21%)
		leucine-rich repeat	185..208	CDD:275380	7/25 (28%)
		leucine-rich repeat	209..232	CDD:275380	5/36 (14%)
		LRR_8	232..289	CDD:290566	11/45 (24%)
		leucine-rich repeat	233..256	CDD:275380	5/22 (23%)
		leucine-rich repeat	257..280	CDD:275380	5/20 (25%)
		LRR_8	280..339	CDD:290566
		leucine-rich repeat	281..304	CDD:275380
		leucine-rich repeat	305..328	CDD:275380
Lgi4	NP_955793.1	leucine-rich repeat	54..77	CDD:275378	7/22 (32%)
		LRR_8	76..136	CDD:290566	24/59 (41%)
		leucine-rich repeat	78..101	CDD:275378	10/22 (45%)
		LRR_4	102..140	CDD:289563	13/37 (35%)
		leucine-rich repeat	102..125	CDD:275378	7/22 (32%)
		leucine-rich repeat	126..149	CDD:275378	6/22 (27%)
		leucine-rich repeat	150..162	CDD:275378	2/11 (18%)
		LRRCT	158..207	CDD:214507	11/57 (19%)
		EPTP	<220..251	CDD:281697	3/4 (75%)
		EPTP	351..392	CDD:281697
		EPTP	396..438	CDD:281697
		EPTP	441..482	CDD:281697
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334965
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930