Protein Alignment CG18095 and FLRT1

DIOPT Version :9

• Sequence 1: NP_001188805.1
• Gene: CG18095 / 34823
• FlyBaseID: FBgn0028872
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001371395.1
• Gene: FLRT1 / 23769
• HGNCID: 3760
• Length: 674
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 131/567 - (23%)
• Similarity: 203/567 - (35%)
• Gaps: 212/567 - (37%)

  Fly    40 LLTSLT--LSNCTLPHV---ENGFFVRFD-----------------HLLHLELQHSGL------- 75
            |:..||  :.:.|.|.|   :|||....|                 :|.:.::.::|:
Human    41 LIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTK 105

  Fly    76 ----------SDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLSKLSVKS 130
                      :|||:|.:|....|:.|.|..||:.:                ::.:.|:::
Human   106 VNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRT----------------IARDSLARI---- 150

  Fly   131 FEQYPQLQQLDLRYNRIS--QIENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGL-HRLSSLSLQH 192
                |.|::|.|..|.:|  .||.|:|.....||.|:|:.|.|:.|..    || |.|..|.|..
Human   151 ----PLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPS----GLPHTLEELRLDD 207

  Fly   193 NRIEFIEMDSFESNTHLRSLRLDQNLL----------SSLQFLSQRGLAR----LVHLNLSSNLL 243
            |||..|.:.:|:....||.|.||.|||          |.||.|::..|.|    ...|||.|..|
Human   208 NRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHL 272

  Fly   244 QKLEPFVFSKNFELQDLDLS---YNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLDSLIAL 305
            |||         .|||..:|   ||.:.|:.:        |||
Human   273 QKL---------YLQDNAISHIPYNTLAKMRE--------LER---------------------- 298

  Fly   306 LQLDISFNLLTTLPDNLFHFNTQLEEIILANN--------------------------------- 337
              ||:|.|.|||||..||.....|.:::|.||
Human   299 --LDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPE 361

  Fly   338 -----KIEEISSQM--MFNQNHLRYIKLSGNAISDAAFLDRLSPSVNRFTLYVDLSSNRLKSLNL 395
                 .|::|:|:|  .|.......:..:....:.:......:|..:.|||.......||...|:
Human   362 KVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTLKAKRPGLRLPDSNI 426

  Fly   396 -----------SSLLHFRYINLADN---NWSCNWLVANLVQKLPNSVNFARPW------TVINNL 440
                       :..:|.:.:. ||:   .|...         ||.| :|...|      ..:.::
Human   427 DYPMATGDGAKTLAIHVKALT-ADSIRITWKAT---------LPAS-SFRLSWLRLGHSPAVGSI 480

  Fly   441 SENTTNVEGIDCIEGGTNRSIILLDVSGVPQPKSDNCDCVVAYDETN 487
            :|  |.|:|        :::..||...   :|||....|:|..:.:|
Human   481 TE--TLVQG--------DKTEYLLTAL---EPKSTYIICMVTMETSN 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380	9/44 (20%)
		LRR_8	64..123	CDD:290566	12/75 (16%)
		leucine-rich repeat	65..88	CDD:275380	7/39 (18%)
		leucine-rich repeat	89..112	CDD:275380	5/22 (23%)
		leucine-rich repeat	113..136	CDD:275380	1/22 (5%)
		LRR_RI	115..384	CDD:238064	85/328 (26%)
		LRR_8	135..195	CDD:290566	24/62 (39%)
		leucine-rich repeat	137..160	CDD:275380	9/24 (38%)
		leucine-rich repeat	161..184	CDD:275380	9/23 (39%)
		LRR_8	184..243	CDD:290566	26/72 (36%)
		leucine-rich repeat	185..208	CDD:275380	8/22 (36%)
		leucine-rich repeat	209..232	CDD:275380	13/32 (41%)
		LRR_8	232..289	CDD:290566	19/63 (30%)
		leucine-rich repeat	233..256	CDD:275380	8/22 (36%)
		leucine-rich repeat	257..280	CDD:275380	7/25 (28%)
		LRR_8	280..339	CDD:290566	18/96 (19%)
		leucine-rich repeat	281..304	CDD:275380	3/22 (14%)
		leucine-rich repeat	305..328	CDD:275380	11/22 (50%)
FLRT1	NP_001371395.1	PRK15370	<58..>329	CDD:185268	91/339 (27%)
		leucine-rich repeat	108..128	CDD:275380	5/19 (26%)
		leucine-rich repeat	129..152	CDD:275380	6/46 (13%)
		leucine-rich repeat	153..178	CDD:275380	9/24 (38%)
		leucine-rich repeat	179..199	CDD:275380	9/23 (39%)
		leucine-rich repeat	200..223	CDD:275380	8/22 (36%)
		leucine-rich repeat	224..249	CDD:275380	10/24 (42%)
		leucine-rich repeat	250..271	CDD:275380	7/20 (35%)
		leucine-rich repeat	272..295	CDD:275380	11/31 (35%)
		leucine-rich repeat	296..319	CDD:275380	14/46 (30%)
		PCC	300..>406	CDD:188093	19/105 (18%)
		FN3	441..505	CDD:214495	18/87 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45712
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100