back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18095 and FMOD

DIOPT Version :10

Sequence 1:	NP_001188805.1	Gene:	CG18095 / 34823	FlyBaseID:	FBgn0028872	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_002014.2	Gene:	FMOD / 2331	HGNCID:	3774	Length:	376	Species:	Homo sapiens

Alignment Length:	291	Identity:	75/291 - (25%)
Similarity:	139/291 - (47%)	Gaps:	46/291 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 TKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLS--KLSVKSFEQYPQLQQLDLRYNRISQ 149
            ::::|:...:|.::|::....:....|..:.|..|.::  |:..|.|.:...|::|.|.:|.:::
Human   105 SRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTR 169

  Fly   150 IENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRL 214
            :....   ...|:.|:|:.||::.:..:...||..|::|.||||.|:  |:.|
Human   170 MPGPL---PRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQ--EVGS------------ 217

  Fly   215 DQNLLSSLQFLSQRGLARLVHLNLSSNLLQKLEPFVFSKNFELQDLDLSYNNITKLNKEALSGLD 279
                       |.|||..|:.|:||.|.|:|:...:.|   .|:.|.:.:||:..:......|..
Human   218 -----------SMRGLRSLILLDLSYNHLRKVPDGLPS---ALEQLYMEHNNVYTVPDSYFRGAP 268

  Fly   280 SLERLNISHNYV--DKIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNTQLEEIILANNKIEEI 342
            .|..:.:|||.:  :.:...:.:| .:||:||:|:|.|..:|.    .||.||.:.|..|:|.|.
Human   269 KLLYVRLSHNSLTNNGLASNTFNS-SSLLELDLSYNQLQKIPP----VNTNLENLYLQGNRINEF 328

  Fly   343 SSQM------MFNQNHLRYIKLSGNAISDAA 367
            |...      :.|.:.|:.::|.||.|..:|
Human   329 SISSFCTVVDVVNFSKLQVLRLDGNEIKRSA 359

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.