DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18095 and lron-2

DIOPT Version :9

Sequence 1:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_505402.1 Gene:lron-2 / 179309 WormBaseID:WBGene00022789 Length:575 Species:Caenorhabditis elegans


Alignment Length:509 Identity:117/509 - (22%)
Similarity:190/509 - (37%) Gaps:153/509 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 PRLSCLQLSKCNNTEVTLIRKTELLTSLTLSNCTLPHVENGFFVRFDHLLHLELQHSGLSD--LD 79
            |||..|:....|...:..:..|..               |.|..| |.||.|||..:.|:|  |.
 Worm   129 PRLRNLRKLYLNRNRINQLSSTAF---------------NAFESR-DLLLKLELAGNRLTDATLG 177

  Fly    80 DFSL-NGLTKLQYLSLSHNNLSSLRSWS-SEPLGALTNLDLSHNMLSKLSVKSFEQYPQLQQLDL 142
            |.:: ..||.||.|||..|:|:|:.|.: ......||||:|..|.::::.|.:.: :|.|..|.|
 Worm   178 DATVFRPLTLLQELSLETNSLTSIPSSALVNQRNTLTNLNLGLNSINEVPVGALD-FPVLSSLSL 241

  Fly   143 RYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDSFESNT 207
            .:|.|:.|...:|.|:.:|:.||:.||:........||.:.:|.:|.:....|..|..::|   .
 Worm   242 EFNGITVIPPQAFQGVPNLQFLYMTGNKFPSWAPEMFRYITQLKTLGIGETPISVIPNNAF---M 303

  Fly   208 HLRSLRLDQNLLSSLQFLSQRGLARLVHLNLSSNLLQKLEPFVFSKNFELQDLDLSYNNITKLNK 272
            |                     :..|:.|.:|...:..:|...|.:..::|.:.|:.|.::::..
 Worm   304 H---------------------IPNLIRLEMSEAAVDTIERGAFQRTPQIQAIVLNKNRLSQVRA 347

  Fly   273 EALSGLDSLERLNISHNYVDKIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNTQLEEIILANN 337
            :...||:.|..:::..|.:|.:......:|.|:..||||:|||.|:|.|:|              
 Worm   348 DFFEGLNDLYSIDLQGNRIDNVQPLGFANLPAISHLDISYNLLQTMPSNVF-------------- 398

  Fly   338 KIEEISSQMMFNQNHLRYIKLSGNAISDAAFLDRLSPSVNRFTLYVDLSSNRLKSLNLSSLLHFR 402
                        ||               :||    |..|          :|            |
 Worm   399 ------------QN---------------SFL----PQPN----------DR------------R 410

  Fly   403 YINLADNNWSCN----WLVANLVQKLPNSVNFARP-WTVINNLSENTTNVEGIDCIEGGTNRSII 462
            .|....|.|.||    |....|...|  .::..:| .|.:...|.|...||              
 Worm   411 VIYACGNPWYCNSELEWFRTLLRDNL--DIDVEKPGCTAVCTSSPNGCPVE-------------- 459

  Fly   463 LLDVSGVPQPKSDNCDCVVAYDETNPSPPPLTWPKIPTDRFDSRSVIIWMLVAI 516
                 |.|....|.|       :.|....||....:        |::.|:::|:
 Worm   460 -----GTPLRSVDFC-------QNNEEAQPLVGRAL--------SMVGWIILAV 493

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380 3/22 (14%)
LRR_8 64..123 CDD:290566 26/62 (42%)
leucine-rich repeat 65..88 CDD:275380 10/25 (40%)
leucine-rich repeat 89..112 CDD:275380 9/23 (39%)
leucine-rich repeat 113..136 CDD:275380 7/22 (32%)
LRR_RI 115..384 CDD:238064 59/268 (22%)
LRR_8 135..195 CDD:290566 18/59 (31%)
leucine-rich repeat 137..160 CDD:275380 8/22 (36%)
leucine-rich repeat 161..184 CDD:275380 7/22 (32%)
LRR_8 184..243 CDD:290566 9/58 (16%)
leucine-rich repeat 185..208 CDD:275380 5/22 (23%)
leucine-rich repeat 209..232 CDD:275380 0/22 (0%)
LRR_8 232..289 CDD:290566 11/56 (20%)
leucine-rich repeat 233..256 CDD:275380 5/22 (23%)
leucine-rich repeat 257..280 CDD:275380 5/22 (23%)
LRR_8 280..339 CDD:290566 16/58 (28%)
leucine-rich repeat 281..304 CDD:275380 4/22 (18%)
leucine-rich repeat 305..328 CDD:275380 11/22 (50%)
lron-2NP_505402.1 leucine-rich repeat 64..84 CDD:275380
leucine-rich repeat 85..109 CDD:275380
LRR_8 86..144 CDD:290566 5/14 (36%)
LRR_RI 109..294 CDD:238064 55/181 (30%)
leucine-rich repeat 110..133 CDD:275380 3/3 (100%)
LRR_8 132..198 CDD:290566 24/81 (30%)
leucine-rich repeat 134..157 CDD:275380 5/37 (14%)
leucine-rich repeat 161..187 CDD:275380 10/25 (40%)
leucine-rich repeat 188..211 CDD:275380 9/22 (41%)
LRR_8 212..270 CDD:290566 21/58 (36%)
leucine-rich repeat 213..235 CDD:275380 7/22 (32%)
leucine-rich repeat 236..259 CDD:275380 8/22 (36%)
leucine-rich repeat 260..283 CDD:275380 7/22 (32%)
LRR_8 282..342 CDD:290566 14/83 (17%)
leucine-rich repeat 284..307 CDD:275380 6/46 (13%)
leucine-rich repeat 308..355 CDD:275380 10/46 (22%)
LRR_8 330..390 CDD:290566 15/59 (25%)
leucine-rich repeat 356..377 CDD:275380 3/20 (15%)
leucine-rich repeat 380..400 CDD:275380 11/45 (24%)
Ca_hom_mod <481..>504 CDD:291464 3/21 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160159443
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.930

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