DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18095 and Dcn

DIOPT Version :9

Sequence 1:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_001177380.1 Gene:Dcn / 13179 MGIID:94872 Length:354 Species:Mus musculus


Alignment Length:305 Identity:72/305 - (23%)
Similarity:133/305 - (43%) Gaps:65/305 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 LELQHSGLSDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPLGALTNLDLSHNMLSKLSVKSFE 132
            |:||::.::::.:.:...|..|..|.|.:|.:|.:...:.:||..|..|.||.|.|.:|.    |
Mouse    81 LDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNQLKELP----E 141

  Fly   133 QYPQ-LQQLDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAH--IDGSFFRGLHRLSSLSLQHNR 194
            :.|: ||:|.:..|.|:::....|:||:::..:.|.||.|.:  |:...|:||..||.:.:    
Mouse   142 KMPRTLQELRVHENEITKLRKSDFNGLNNVLVIELGGNPLKNSGIENGAFQGLKSLSYIRI---- 202

  Fly   195 IEFIEMDSFESNTHLRSLRLDQNLLSSLQFLSQRGLARLVHLNLSSNLLQKLEPFVFSKNFELQD 259
                      |:|::.:  :.|.|.:|                                   |.:
Mouse   203 ----------SDTNITA--IPQGLPTS-----------------------------------LTE 220

  Fly   260 LDLSYNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLDSLIALLQLDISFNLLTTLPDNLFH 324
            :.|..|.|||::..:|.||.:|.:|.:|.|.:..:.:.||.::..|.:|.:..|.|..:|..|..
Mouse   221 VHLDGNKITKVDAPSLKGLINLSKLGLSFNSITVMENGSLANVPHLRELHLDNNKLLRVPAGLAQ 285

  Fly   325 FNTQLEEIILANNKIEEISSQMMFNQNH------LRYIKLSGNAI 363
             :..::.:.|.||.|..:.........|      ...:.|.||.:
Mouse   286 -HKYIQVVYLHNNNISAVGQNDFCRAGHPSRKASYSAVSLYGNPV 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380
LRR_8 64..123 CDD:290566 16/54 (30%)
leucine-rich repeat 65..88 CDD:275380 4/19 (21%)
leucine-rich repeat 89..112 CDD:275380 7/22 (32%)
leucine-rich repeat 113..136 CDD:275380 8/22 (36%)
LRR_RI 115..384 CDD:238064 60/258 (23%)
LRR_8 135..195 CDD:290566 19/62 (31%)
leucine-rich repeat 137..160 CDD:275380 8/22 (36%)
leucine-rich repeat 161..184 CDD:275380 8/24 (33%)
LRR_8 184..243 CDD:290566 7/58 (12%)
leucine-rich repeat 185..208 CDD:275380 3/22 (14%)
leucine-rich repeat 209..232 CDD:275380 3/22 (14%)
LRR_8 232..289 CDD:290566 12/56 (21%)
leucine-rich repeat 233..256 CDD:275380 0/22 (0%)
leucine-rich repeat 257..280 CDD:275380 9/22 (41%)
LRR_8 280..339 CDD:290566 15/58 (26%)
leucine-rich repeat 281..304 CDD:275380 6/22 (27%)
leucine-rich repeat 305..328 CDD:275380 6/22 (27%)
DcnNP_001177380.1 LRRNT 48..80 CDD:214470
leucine-rich repeat 57..77 CDD:275380
LRR 1 68..88 3/6 (50%)
leucine-rich repeat 78..101 CDD:275380 4/19 (21%)
LRR_RI <79..285 CDD:238064 64/258 (25%)
LRR_8 79..136 CDD:290566 16/54 (30%)
LRR 2 89..112 5/22 (23%)
leucine-rich repeat 102..125 CDD:275380 7/22 (32%)
LRR 3 113..136 8/22 (36%)
leucine-rich repeat 126..146 CDD:275380 9/23 (39%)
LRR 4 137..157 7/23 (30%)
LRR_8 145..207 CDD:290566 20/75 (27%)
leucine-rich repeat 147..170 CDD:275380 8/22 (36%)
LRR 5 158..181 6/22 (27%)
leucine-rich repeat 171..196 CDD:275380 8/24 (33%)
LRR 6 182..207 8/38 (21%)
leucine-rich repeat 197..217 CDD:275380 6/35 (17%)
LRR 7 208..228 6/56 (11%)
LRR_8 216..276 CDD:290566 19/94 (20%)
leucine-rich repeat 218..241 CDD:275380 9/22 (41%)
LRR 8 229..252 9/22 (41%)
leucine-rich repeat 242..265 CDD:275380 6/22 (27%)
LRR 9 253..276 5/22 (23%)
LRR_8 264..>307 CDD:290566 10/43 (23%)
LRR 10 277..299 5/22 (23%)
leucine-rich repeat 289..309 CDD:275380 4/19 (21%)
LRR 11 300..329 4/28 (14%)
LRR 12 330..354 72/305 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45712
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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