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Protein Alignment CG18095 and PODN

DIOPT Version :10

Sequence 1:	NP_001188805.1	Gene:	CG18095 / 34823	FlyBaseID:	FBgn0028872	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_714914.3	Gene:	PODN / 127435	HGNCID:	23174	Length:	613	Species:	Homo sapiens

Alignment Length:	492	Identity:	115/492 - (23%)
Similarity:	197/492 - (40%)	Gaps:	140/492 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 DHLLHLELQHSGLSDLDDFSLNGLTKLQYLSLSHNNLSSLRSWSSEPLGALTNL----------- 116
            :|..||.||::.|..:....|:.|.:|:.|:|.:|.|:| |....:....||||
Human    96 EHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTS-RGLPEKAFEHLTNLNYLYLANNKLT 159

  Fly   117 -------------DLSHNMLSKLSVKSFEQYPQLQQLDLRYNRISQ--IENDSFDGLSHLKHLYL 166
                         |.:.|.|:|:...:|.|.|.|:.:.|..|:::.  :.::.|:|.|:::.|.|
Human   160 LAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLIL 224

  Fly   167 NGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRLDQNL------------- 218
            :.|.|.|:.......|::   |.|::|::|.|...:|...:.||.|.|..|.
Human   225 SSNFLRHVPKHLPPALYK---LHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWK 286

  Fly   219 LSSLQF--LSQRGLAR----------LVHLN----------------------LSSNLL--QKLE 247
            ||||::  ||...|:|          |:||.                      |.||.|  |.:.
Human   287 LSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIH 351

  Fly   248 PFVFSKNFELQDLDLSYNN----------------------ITKLNKEALSGLDSLERLNISHNY 290
            |..|.....|..:.| |||                      ||.:.:|..:....||.||:|:|.
Human   352 PLAFQGLKRLHTVHL-YNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNR 415

  Fly   291 V--DKIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNTQLEEIILANNKIEEISSQMMFNQNHL 353
            :  .:::.::...|..|..||:|.|.|.|||..|   ...:..:.:..|::..::...:.....|
Human   416 ITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGL---PRNVHVLKVKRNELAALARGALVGMAQL 477

  Fly   354 RYIKLSGNAISDAAFLDRLSPSVNRFTLYVDLSSNRLKSLNLSSLLHFRYINLADNNWSCNWLVA 418
            |.:.|:.|.:...|    |.|..     :|||:             |.:.:::|.|.      :.
Human   478 RELYLTSNRLRSRA----LGPRA-----WVDLA-------------HLQLLDIAGNQ------LT 514

  Fly   419 NLVQKLPNSVNFA-----RPWTVINNLSENTTNVEGI 450
            .:.:.||.|:.:.     :...|..|..::|.|::||
Human   515 EIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGI 551

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.