DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18095 and CHAD

DIOPT Version :9

Sequence 1:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster
Sequence 2:XP_011522516.1 Gene:CHAD / 1101 HGNCID:1909 Length:440 Species:Homo sapiens


Alignment Length:327 Identity:89/327 - (27%)
Similarity:142/327 - (43%) Gaps:66/327 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 DLSHNMLSKLSVKSFEQYPQLQQ----LDLRYNRISQIENDSFDGLSHLKHLYLNGNQLAHIDGS 177
            ||.|.:..|:.:   ::.|::.:    |:|:.|....:..:||..:.:|..|:|...|:..:...
Human   113 DLQHVICDKVGL---QKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAG 174

  Fly   178 FFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRLDQNLLSSLQFLSQRG----LARLVHLNL 238
            .||||.:|..|.|.||.|..:...:|:..|.|..|.||.|.::.|    .||    |..|..|.|
Human   175 AFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTEL----PRGLLSPLVNLFILQL 235

  Fly   239 SSNLLQKLEPFVFSKNFELQDLDLSYNNITKLNKEALSGLDSLERLNISHNYVDKIYDESLDSLI 303
            ::|.:::|....|....:|:.|.||.|.::.|...||..:::|.:.::..|.:......:|..|.
Human   236 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLR 300

  Fly   304 ALLQLDISFNLLTTLPDNLFH-FNTQLEEIILANNKIEEISSQMMFNQNHLRYIKLSGNAISDAA 367
            .:.:|.:|.|.|.::|||.|. |...||.:.|.|..:|:                     .||.|
Human   301 VVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEK---------------------FSDGA 344

  Fly   368 FLDRLSPSVNRFTL-YVDLSSNRLKSL-------NLSSLLHFRYINLADNNWSC--------NWL 416
            ||       ...|| :|.|.:|||..|       :|.:|.      |.:|.|.|        .||
Human   345 FL-------GVTTLKHVHLENNRLNQLPSNFPFDSLETLA------LTNNPWKCTCQLRGLRRWL 396

  Fly   417 VA 418
            .|
Human   397 EA 398

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380
LRR_8 64..123 CDD:290566 3/5 (60%)
leucine-rich repeat 65..88 CDD:275380
leucine-rich repeat 89..112 CDD:275380
leucine-rich repeat 113..136 CDD:275380 4/18 (22%)
LRR_RI 115..384 CDD:238064 74/276 (27%)
LRR_8 135..195 CDD:290566 19/63 (30%)
leucine-rich repeat 137..160 CDD:275380 5/26 (19%)
leucine-rich repeat 161..184 CDD:275380 8/22 (36%)
LRR_8 184..243 CDD:290566 21/62 (34%)
leucine-rich repeat 185..208 CDD:275380 7/22 (32%)
leucine-rich repeat 209..232 CDD:275380 9/26 (35%)
LRR_8 232..289 CDD:290566 15/56 (27%)
leucine-rich repeat 233..256 CDD:275380 6/22 (27%)
leucine-rich repeat 257..280 CDD:275380 8/22 (36%)
LRR_8 280..339 CDD:290566 17/59 (29%)
leucine-rich repeat 281..304 CDD:275380 4/22 (18%)
leucine-rich repeat 305..328 CDD:275380 9/23 (39%)
CHADXP_011522516.1 LRRNT 104..130 CDD:279764 5/19 (26%)
leucine-rich repeat 134..157 CDD:275380 5/22 (23%)
LRR_8 156..216 CDD:290566 21/59 (36%)
leucine-rich repeat 158..181 CDD:275380 8/22 (36%)
LRR_RI <171..363 CDD:238064 65/223 (29%)
leucine-rich repeat 182..205 CDD:275380 7/22 (32%)
LRR_8 204..264 CDD:290566 21/63 (33%)
leucine-rich repeat 206..229 CDD:275380 9/26 (35%)
leucine-rich repeat 230..253 CDD:275380 6/22 (27%)
leucine-rich repeat 254..277 CDD:275380 8/22 (36%)
leucine-rich repeat 278..301 CDD:275380 4/22 (18%)
LRR_8 302..361 CDD:290566 24/86 (28%)
leucine-rich repeat 302..325 CDD:275380 9/22 (41%)
leucine-rich repeat 327..350 CDD:275380 10/50 (20%)
leucine-rich repeat 351..373 CDD:275380 7/21 (33%)
LRRCT 381..428 CDD:214507 6/18 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141289
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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