Protein Alignment CG18095 and Chadl

DIOPT Version :9

• Sequence 1: NP_001188805.1
• Gene: CG18095 / 34823
• FlyBaseID: FBgn0028872
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_038936217.1
• Gene: Chadl / 100910434
• RGDID: 6504353
• Length: 747
• Species: Rattus norvegicus
• Alignment Length: 698
• Identity: 148/698 - (21%)
• Similarity: 225/698 - (32%)
• Gaps: 261/698 - (37%)

  Fly     7 SLLLLIFSFSPRLS-----CLQLSKCNN------------TEV-----TLIRKTEL--------- 40
            :||||:...||..:     |.|...|:|            |||     .|.::.:|
  Rat    18 TLLLLMMFLSPAWNVAAQRCPQTCVCDNSRRHVTCQHQNLTEVPDTIPELTQRLDLQGNMLKVIP 82

  Fly    41 ---------LTSLTLSNCTLPHVENGFFVRFDHLLHLELQHSGLSDLDDFSLNGLTKLQYLSLSH 96
                     ||.|.|.:|.:..|..|.|.....||.|.|..:.||.|...:|:||..|:.|.|..
  Rat    83 PAAFQDLPYLTHLDLQHCQVEQVAEGAFRGLGRLLFLNLASNRLSSLPQEALDGLGSLRRLELER 147

  Fly    97 NNLSSLRSWSSEPLGALTNLDLSHNMLSKLSVKSFEQYPQLQQLDLRYNRISQIENDSFDGLSHL 161
            |.|..||..:...||:|..|:|:||.|..|...:|:...:.:.|.|.:|.:|.:..::..||..|
  Rat   148 NMLEELRPGTFGALGSLATLNLAHNALVYLPAMAFQGLMRTRWLQLSHNALSVLAPEALAGLPVL 212

  Fly   162 KHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRLDQNLLSSLQFLS 226
            :.|.|:.|:|..:.|:.......|:.|.|.||.:.:...:...:...||.|.||.   .|||.|.
  Rat   213 RRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDH---GSLQALG 274

  Fly   227 QRGLA---RLVHLNLSSNLLQKLEPFV-------------------------------------- 250
            .|..|   ||..|:|..|.|..|.|..
  Rat   275 PRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCACHARPLLEWLVRARVRSDGA 339

  Fly   251 ----------------------------------------------------------------- 250
                                                                             
  Rat   340 CRGPRRLRGETLDTLRPSDLRCPGDAAEDEDEDRPAGPRSPPRSLHEEARWATPCPPACVCVGET 404

  Fly   251 ----------------FSKNFELQD----------------------LDLSYNNITKLNKEALSG 277
                            |..:.:|.|                      |.|.:..|.:|...||:|
  Rat   405 RHSACDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGIAELEPGALAG 469

  Fly   278 LDSLERLNISHNYVDKIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNTQLEEIILANNKIEEI 342
            ||.|..|.:|:|.:..:...:|:....|..|.:..|....:|........:|..:.|.:|.::.:
  Rat   470 LDGLVYLYLSNNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGAALRALPRLFSLHLQDNAVDRL 534

  Fly   343 SSQMMFNQNHLRYIKLSGNAISDAAFLDRLSPSVNRFTLYVDLSSNR------------LKSLNL 395
            :...:.....||.:.||||.|:..: ...|.|:.....|::|.:..|            ||.|.|
  Rat   535 APGDLAGARALRGLYLSGNHITQVS-PGALGPARELEKLHLDRNQLRQVPTGALEGLPALKELQL 598

  Fly   396 S----SLLH---FR---------YINLAD-------------NNWSCNWLVANLVQKLPNSVNFA 431
            |    ..||   |:         ::|.:|             ......:|..|.:|.||     |
  Rat   599 SRNPFRALHDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLQGLYLQQNQLQSLP-----A 658

  Fly   432 RPWTVINNLSENTTNVEGIDCIEGGTNRSIILLDVSGVPQPKSDNCDC 479
            ..|            :.|::           |:|:||.|    .:|||
  Rat   659 PMW------------LSGLE-----------LIDLSGNP----FHCDC 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18095	NP_001188805.1	leucine-rich repeat	41..64	CDD:275380	8/22 (36%)
		LRR_8	64..123	CDD:290566	24/58 (41%)
		leucine-rich repeat	65..88	CDD:275380	10/22 (45%)
		leucine-rich repeat	89..112	CDD:275380	8/22 (36%)
		leucine-rich repeat	113..136	CDD:275380	8/22 (36%)
		LRR_RI	115..384	CDD:238064	77/412 (19%)
		LRR_8	135..195	CDD:290566	17/59 (29%)
		leucine-rich repeat	137..160	CDD:275380	6/22 (27%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		LRR_8	184..243	CDD:290566	21/61 (34%)
		leucine-rich repeat	185..208	CDD:275380	5/22 (23%)
		leucine-rich repeat	209..232	CDD:275380	11/25 (44%)
		LRR_8	232..289	CDD:290566	23/197 (12%)
		leucine-rich repeat	233..256	CDD:275380	8/141 (6%)
		leucine-rich repeat	257..280	CDD:275380	10/44 (23%)
		LRR_8	280..339	CDD:290566	12/58 (21%)
		leucine-rich repeat	281..304	CDD:275380	5/22 (23%)
		leucine-rich repeat	305..328	CDD:275380	4/22 (18%)
Chadl	XP_038936217.1	PLN00113	30..>555	CDD:215061	110/527 (21%)
		leucine-rich repeat	48..66	CDD:275380	3/17 (18%)
		leucine-rich repeat	68..91	CDD:275380	1/22 (5%)
		leucine-rich repeat	92..115	CDD:275380	8/22 (36%)
		leucine-rich repeat	116..139	CDD:275380	10/22 (45%)
		leucine-rich repeat	140..163	CDD:275380	8/22 (36%)
		leucine-rich repeat	164..187	CDD:275380	8/22 (36%)
		leucine-rich repeat	188..211	CDD:275380	6/22 (27%)
		leucine-rich repeat	212..235	CDD:275380	6/22 (27%)
		leucine-rich repeat	236..259	CDD:275380	5/22 (23%)
		leucine-rich repeat	260..283	CDD:275380	11/25 (44%)
		leucine-rich repeat	306..345	CDD:275380	0/38 (0%)
		leucine-rich repeat	425..448	CDD:275380	2/22 (9%)
		PPP1R42	446..603	CDD:411060	38/157 (24%)
		leucine-rich repeat	449..472	CDD:275380	8/22 (36%)
		leucine-rich repeat	473..496	CDD:275380	5/22 (23%)
		leucine-rich repeat	497..520	CDD:275380	4/22 (18%)
		leucine-rich repeat	521..544	CDD:275380	3/22 (14%)
		leucine-rich repeat	545..568	CDD:275380	9/23 (39%)
		leucine-rich repeat	569..592	CDD:275380	3/22 (14%)
		LRR_8	591..653	CDD:404697	12/61 (20%)
		leucine-rich repeat	593..617	CDD:275380	8/23 (35%)
		leucine-rich repeat	618..641	CDD:275380	2/22 (9%)
		leucine-rich repeat	643..665	CDD:275380	7/38 (18%)
		leucine-rich repeat	666..677	CDD:275378	5/25 (20%)
		LRRCT	673..721	CDD:214507	4/11 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334961
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840