Protein Alignment hll and FAA2

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_010931.3
• Gene: FAA2 / 856734
• SGDID: S000000817
• Length: 744
• Species: Saccharomyces cerevisiae
• Alignment Length: 645
• Identity: 146/645 - (22%)
• Similarity: 252/645 - (39%)
• Gaps: 138/645 - (21%)

  Fly    97 VGILAFNCPEWFFAEFGALRAGAVVAGVYPS----------NSAEA---------VHHVLAT--- 139
            |.||:.|.|||...:............:|.:          |..||         ::|||..
Yeast   166 VAILSHNNPEWILTDLACQAYSLTNTALYETLGPNTSEYILNLTEAPILIFAKSNMYHVLKMVPD 230

  Fly   140 ---GESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQ-TFSSE 200
               ..:.||:  |.....:||.:.|.|..:|.                     ..|.|: ||.|.
Yeast   231 MKFVNTLVCM--DELTHDELRMLNESLLPVKC---------------------NSLNEKITFFSL 272

  Fly   201 LKEELLARESRIRA-----NECAMLIFTSGTVGMPKAVMLSHDNL------VFDTKSAAAHMQDI 254
            .:.|.:...::|.|     :....:.|||||.|:||.|.:||.|:      .|.|.......::.
Yeast   273 EQVEQVGCFNKIPAIPPTPDSLYTISFTSGTTGLPKGVEMSHRNIASGIAFAFSTFRIPPDKRNQ 337

  Fly   255 QVGKESFVSYLPLSHVAAQI---FDVFLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPR 316
            |:..   :.:|||:|:..::   :|:.:|..    :.|..|.. ...|::..:..:|..:..|||
Yeast   338 QLYD---MCFLPLAHIFERMVIAYDLAIGFG----IGFLHKPD-PTVLVEDLKILKPYAVALVPR 394

  Fly   317 VFEKLQERLVAAEAKA---RPYSRLLLARARAAVAEHQTTLMAGKSPSIYGNAKYWLACRVVKPI 378
            :..:.:..:..|..|:   |..:..:|....|     :.|...|...||.....|...  ::..|
Yeast   395 ILTRFEAGIKNALDKSTVQRNVANTILDSKSA-----RFTARGGPDKSIMNFLVYHRV--LIDKI 452

  Fly   379 REMIGVDNCRVFFTGGAPTSEELKQFF-LGLDIALGECYGMSETSGAITLN----VDISNLYSAG 438
            |:.:|:.|.....||.||.|::...|. ..|||.:.:.||::||...:.|:    .|:.:..:.|
Yeast   453 RDSLGLSNNSFIITGSAPISKDTLLFLRSALDIGIRQGYGLTETFAGVCLSEPFEKDVGSCGAIG 517

  Fly   439 QACE----GVTLKIHEPDCNGQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKG 499
            .:.|    .|....:..|.:.:||:.:||..||..|...|::|.:.|.:|||..:||:.:||.||
Yeast   518 ISAECRLKSVPEMGYHADKDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKG 582

  Fly   500 NLIISGRLKELIITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGI 564
            .:.:..|:|.....|.||.|.|..||.:.....|.::.:.:.||         .|||......|:
Yeast   583 RISVIDRVKNFFKLAHGEYIAPEKIENIYLSSCPYITQIFVFGD---------PLKTFLVGIVGV 638

  Fly   565 PLDALR-------EETIEWLRDLDIHETRLSELLNIPADLQLPNDTAALAATLEITAKPKLLEAI 622
            .:||.:       .|...|.:::      |.|.||....|:
Yeast   639 DVDAAQPILAAKHPEVKTWTKEV------LVENLNRNKKLR------------------------ 673

  Fly   623 EEGIKRANKY--AISNAQKVQKFALIAHEFSVATGELGPTLKIRRNIVHAKYAKVIERLY 680
            :|.:.:.||.  .:...:|:....:.....::....:.||.||:|......:...:::||
Yeast   674 KEFLNKINKCTDGLQGFEKLHNIKVGLEPLTLEDDVVTPTFKIKRAKASKFFKDTLDQLY 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	144/643 (22%)
FAA2	NP_010931.3	LC-FACS_euk	126..734	CDD:341250	146/645 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810