Protein Alignment hll and FAA4

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_013974.1
• Gene: FAA4 / 855288
• SGDID: S000004860
• Length: 694
• Species: Saccharomyces cerevisiae
• Alignment Length: 661
• Identity: 151/661 - (22%)
• Similarity: 261/661 - (39%)
• Gaps: 112/661 - (16%)

  Fly    67 WTTLTFGEYQERVEQAALMLLSVGVEE--RSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPS-N 128
            :.|:|:.|....:......|:.:||:.  .:...|.|....:|.....|.:..|..|...|.: .
Yeast    97 YITMTYEEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIPVVTAYDTLG 161

  Fly   129 SAEAVHHVLATGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPG-------- 185
            .:..:|.::.|  .||.:..|.|.::||....:....:|.||. :.|.:.....:.|
Yeast   162 ESGLIHSMVET--DSVAIFTDNQLLSKLAVPLKTAKNVKFVIH-NEPIDPSDKRQNGKLYKAAKD 223

  Fly   186 -------------YFSWQKLQEQTFSSELKEELLARESRIRANECAMLIFTSGTVGMPKAVMLSH 237
                         .:|:.::.|  ...:.|:|:.....:.....|.|  :|||:.|.||.|:|:|
Yeast   224 AVDKIKEVRPDIKIYSFDEIIE--IGKKAKDEVELHFPKPEDPACIM--YTSGSTGTPKGVVLTH 284

  Fly   238 DNLVFDTKSAAAHMQDIQVG-KESFVSYLPLSHVAAQIFDV-------FLGLSHAGCVTFADKDA 294
            .|:|... ....|.....:| .:..:::|||:|:....|:.       .||.::...:|......
Yeast   285 YNIVAGI-GGVGHNVIGWIGPTDRIIAFLPLAHIFELTFEFEAFYWNGILGYANVKTLTPTSTRN 348

  Fly   295 LKGTLIKTFRKARPTKMFGVPRVFEKLQERLVAAEAKARPYSRLLLARARAAVAEHQTTLMAGKS 359
            .:|.|:    :.:||.|.||..|:|.:::.::|...:...:|:.|.           .|:.|.|.
Yeast   349 CQGDLM----EFKPTVMVGVAAVWETVRKGILAKINELPGWSQTLF-----------WTVYALKE 398

  Fly   360 PSIYGNAKYWLACRVVKPIREMIGVDNCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSE-TSG 423
            .:|  .....|:..:.|.|||..| .|.|....||:..|.:.::|...|...:...||::| .:.
Yeast   399 RNI--PCSGLLSGLIFKRIREATG-GNLRFILNGGSAISIDAQKFLSNLLCPMLIGYGLTEGVAN 460

  Fly   424 AITLNVDISNLYSAGQACEGVTLKIHEPD------CNGQGEILMRGRLVFMGYLGLPDKTEETVK 482
            |..|..:..:...||.....:|.|:.:.:      .|.|||:|.:|..:...|...|::|.....
Yeast   461 ACVLEPEHFDYGIAGDLVGTITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKNPEETAAAFT 525

  Fly   483 EDGWLHSGDLGYIDPKGNLIISGRLKELIITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKY 547
            :|||..:||:....|||.:.|..|.|.|:.|..||.|....:|.:.:.. |.|.|:.:..|..|.
Yeast   526 DDGWFRTGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESIYRSN-PYVQNICVYADENKV 589

  Fly   548 LTV-----LLSLKTKCDAKTGIPLDALREETIEWLRDLDIHETRLSELLNIPADLQLPNDTAALA 607
            ..|     .|...:|...:.||.:..   |.:|..    |||.:|.:               |:.
Yeast   590 KPVGIVVPNLGHLSKLAIELGIMVPG---EDVESY----IHEKKLQD---------------AVC 632

  Fly   608 ATLEITAKPKLLEAIEE--GIKRANKYAISNAQKVQKFALIAHEFSVATGELGPTLKIRRNIVHA 670
            ..:..|||.:.|..||.  ||                 .....|::...|.:....|::|..:.|
Yeast   633 KDMLSTAKSQGLNGIELLCGI-----------------VFFEEEWTPENGLVTSAQKLKRRDILA 680

  Fly   671 KYAKVIERLYK 681
            .....:||:||
Yeast   681 AVKPDVERVYK 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	149/658 (23%)
FAA4	NP_013974.1	LC_FACS_euk1	96..678	CDD:341294	146/646 (23%)
		PRK04319	<230..>285	CDD:235279	14/58 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810