Protein Alignment hll and Acsbg3

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_084417.1
• Gene: Acsbg3 / 78625
• MGIID: 1925875
• Length: 705
• Species: Mus musculus
• Alignment Length: 699
• Identity: 217/699 - (31%)
• Similarity: 341/699 - (48%)
• Gaps: 61/699 - (8%)

  Fly     4 LKPATSYRSTSLHDAVKLRLDEPSSFSQTVPPQTIPEFFKESCEKYSDLPALVWETPGSG-NDGW 67
            |.|.:||.::.....|:||:.:....::  ||.|:|:....:..|||...|:     ||. ...|
Mouse    43 LTPGSSYWTSKREGQVQLRMGKDPLDNE--PPVTVPDLIMSAATKYSHYLAI-----GSKYKKSW 100

  Fly    68 TTLTFGEYQERVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEA 132
            ..||:.||.|...:||...|.||:|....|||:..|..||..|..||:.||.:..|:..|.|.:|
Mouse   101 QLLTYIEYYEACRRAAKAFLKVGLERFHGVGIMGINSSEWVIASIGAIMAGGISVGILSSISPKA 165

  Fly   133 VHHVLATGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQE--Q 195
            ...:..|.|..:.|||:.:|:.|:..|:..|..|||:||..   |...:.:|..:||:...:  .
Mouse   166 CQVIAETSEMDIFVVDNDRQLQKINQIQGYLKHLKAIIQYR---EDIQEAQPNLYSWKGFLDLAD 227

  Fly   196 TFSSELKEELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDI-----Q 255
            ..|.|..::::   ..::.|:|..|::..||.|..||:||||||:.:.|   ||.:|.:     .
Mouse   228 GISDEKLDKII---DTLKPNQCCALVYNQGTTGPSKAIMLSHDNITWTT---AAIVQSLGFKCPP 286

  Fly   256 VGKESFVSYLPLSHVAAQIFDVFLGLSHAGCVTFADKDALK----------GTLIKTFRKARPTK 310
            .|:|..||||||.....||.||::.:|.||.|.|...|:.|          |.|::..|:.:||.
Mouse   287 QGQEILVSYLPLCFPGIQILDVWVAISVAGTVYFPSLDSGKWSGLPRTPGTGFLMELLREVQPTT 351

  Fly   311 MFGVPRVFEKLQERLVAAEAKARPYSRLLLARARAAVAEHQTTLMAGK--SPSIYGNAKYWLACR 373
            ..|:|.|::::.:.|......:..:.|.:...|..........||.|:  .|..:|.||.....|
Mouse   352 FCGIPWVWDRMLDSLKTKFLDSTAFRRRIDHWAMRMGLHTNKKLMMGEIHQPLCFGLAKRLTFER 416

  Fly   374 VVKPIREMIGVDNCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSETSGAITL-NVDISNLYSA 437
            .    |:.:|:::|:.|...|.........|||.::|.:.|.||:||.:|..|: |:....:.||
Mouse   417 A----RKFLGLNHCQQFLNMGMGLPSGTLDFFLSVNIPIMELYGLSECTGLHTVSNLQAYRILSA 477

  Fly   438 GQACEGVTLKIHEPDCNGQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLI 502
            |:|......|:.:.:.:|.|.:.:.||.:|||||.....||..|...||||:.|||::|....|.
Mouse   478 GKALPKTHTKVEKENKDGIGNLCIWGRHIFMGYLRDKQSTERKVDTHGWLHTNDLGFLDFDKFLY 542

  Fly   503 ISGRLKELIITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLD 567
            :.|...:||..:.||.:.|..|||.::..:|.|...:|:|....||..||:||.:.:.:||....
Mouse   543 VMGNNNDLIKLSSGEMVNPYPIEERVRTRIPIVRYAMLVGQDAPYLCALLTLKCQINPETGEARS 607

  Fly   568 ALREETIEWLRDLDIHETRLSELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKY 632
            .|..|.:...|.|....|.||::|                    ....|.:.|.|.:||:..|..
Mouse   608 NLTSEVVACCRKLRSQSTWLSDVL--------------------YDRDPLVTEFINQGIEDVNSE 652

  Fly   633 AISNAQKVQKFALIAHEFSVATGELGPTLKIRRNIVHAKYAKVIERLYK 681
            |.:...|:.|:.::.::|||..|||||..|:.|:||...|.:.|::||:
Mouse   653 APTMGAKIIKWVILDNDFSVDGGELGPMSKMNRSIVVKIYQEEIQKLYE 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	199/638 (31%)
Acsbg3	NP_084417.1	FAA1	74..701	CDD:223953	207/664 (31%)
		ACSBG_like	95..700	CDD:213299	198/637 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839174
Domainoid	1	1.000	128	1.000	Domainoid score	I5288
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D218492at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101481
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.710