Protein Alignment hll and Acsl4

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_997508.1
• Gene: Acsl4 / 50790
• MGIID: 1354713
• Length: 711
• Species: Mus musculus
• Alignment Length: 758
• Identity: 169/758 - (22%)
• Similarity: 314/758 - (41%)
• Gaps: 185/758 - (24%)

  Fly     5 KPATSYRSTSLHDAVKLRLDEPSSFSQTVPPQTIPEFFKESCEKYSDLPAL-------------- 55
            ||.:.|||.:..|::.: :|.|.:       .|:.:.|..:..|:....:|
Mouse    54 KPGSPYRSVTHFDSLAV-IDIPGA-------DTLDKLFDHAVAKFGKKDSLGTREILSEENEMQP 110

  Fly    56 ---VWETPGSGNDGWTTLTFGEYQERVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRA 117
               |::....||..|  :.:.|...||......|.::|::.::::.|......||..|.....:.
Mouse   111 NGKVFKKLILGNYKW--INYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKY 173

  Fly   118 GAVVAGVYPSNSAEAVHHVLATGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDH 182
            ...:..:|.:...|||.|.|...|:|..:.......:||:|....:..:|.:|        :||:
Mouse   174 NFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHII--------YVDN 230

  Fly   183 E-------PGYFSWQKLQEQTFSSELKEELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNL 240
            :       |.......:|.........|.|....||...::.|::::|||:.|.||.||:.|.||
Mouse   231 KTINRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNL 295

  Fly   241 VFDTKSAAAHMQDIQVGKESFVSYLPLSHV---AAQI--FDVFLGLSHAGCVTFAD-----KDAL 295
            :.........:..:. .|::::.||||:||   .|:|  |.....:.::..:|.:|     |...
Mouse   296 IAGMTGQCERIPGLG-PKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGS 359

  Fly   296 KG--TLIKTFRKARPTKMFGVPRVFEKLQERLVAAEAKARPYSRLLLARARAAVAEHQTTLMAGK 358
            ||  |::|      ||.|..||.:.:::.:. |.::.:...|.:             :|....|.
Mouse   360 KGDCTVLK------PTLMAAVPEIMDRIYKN-VMSKVQEMNYVQ-------------KTLFKIGY 404

  Fly   359 SPSIYGNAKYWLA--CRVV--KPIREMIGVDNCRVFFTGGAPTSEELKQFFLGLDIA----LGEC 415
            ...:....|.:.|  |.::  |.::.::| .|.|:..:||||.|.:..:|   :::.    :|:.
Mouse   405 DYKLEQIKKGYDAPLCNLILFKKVKALLG-GNVRMMLSGGAPLSPQTHRF---MNVCFCCPIGQG 465

  Fly   416 YGMSETSGAITLNVDISNLYSAGQ------ACEGVTLK--------IHEPDCNGQGEILMRGRLV 466
            ||::|:.||.|: .:::: |:.|:      .|| :.||        :|:.. |.:|||::.|:.:
Mouse   466 YGLTESCGAGTV-TEVTD-YTTGRVGAPLICCE-IKLKDWQEGGYTVHDKP-NPRGEIVIGGQNI 526

  Fly   467 FMGYLGLPDKTEE--TVKEDG--WLHSGDLGYIDPKGNLIISGRLKELIITAGGENIPPVHIEEL 527
            .|||....:||.|  .|.|:|  |..:||:|...|.|.|.|..|.|:|:....||.:....:|..
Mouse   527 SMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAA 591

  Fly   528 IKKELPCVSNVL------------LIGDHRKYLTVLLSLKTKCDAKTGIPLDALREETIE--WLR 578
            : |..|.:.|:.            .:..::|.||:|                 .:::.:|  |:
Mouse   592 L-KNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLL-----------------AQQKGVEGSWV- 637

  Fly   579 DLDIHETRLSELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKYAISNAQKVQKF 643
                      ::.|.||                  .:.::|:.|.|.         :||.|:::|
Mouse   638 ----------DICNNPA------------------MEAEILKEIREA---------ANAMKLERF 665

  Fly   644 ------ALIAHEFSVATGELGPTLKIRRNIVHAKYAKVIERLY 680
                  .|....::..||.:....|::|..:...|.|.|||:|
Mouse   666 EIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMY 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	155/682 (23%)
Acsl4	NP_997508.1	LC_FACS_euk1	121..696	CDD:341294	150/669 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900