Protein Alignment hll and Acsl5

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_082252.1
• Gene: Acsl5 / 433256
• MGIID: 1919129
• Length: 683
• Species: Mus musculus
• Alignment Length: 689
• Identity: 177/689 - (25%)
• Similarity: 289/689 - (41%)
• Gaps: 127/689 - (18%)

  Fly    36 QTIPEFFKESCEKYSDLPALVWETPGSGNDGWTTLTFGEYQERVEQAALMLLSVGVEERSS--VG 98
            :|:.|.|:.......:.|.|.:..|   |..:..:::.:..:|.|.....||..|.:....  ||
Mouse    75 KTLYENFQRGLAVSDNGPCLGYRKP---NQPYKWISYKQVSDRAEYLGSCLLHKGYKSSQDQFVG 136

  Fly    99 ILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVLATGESSVCVVDDAQQMAKL--RAIKE 161
            |.|.|.|||..:|........|...:|.:...||:..|:...:..|.:.|..|:...|  ...|.
Mouse   137 IFAQNRPEWVISELACYTYSMVAVPLYDTLGTEAIIFVINRADIPVVICDTPQKATMLVENVEKG 201

  Fly   162 RLPRLKAVIQLHGPF-------------EAFVDHEPGYFSWQKLQEQTFSSELKEELLARESRIR 213
            ..|.||.:| |..||             |....|:.     :.:.::.|...:..         :
Mouse   202 LTPGLKTII-LMDPFDDDLMKRGEKCGVEMLSLHDA-----ENIGKENFKKPVPP---------K 251

  Fly   214 ANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDI--QVGKESFVSYLPLSHVAAQIFD 276
            ..:.:::.|||||.|.||..||:|:|:|.:..:....::.|  ....:..:|||||:|:..::..
Mouse   252 PEDLSVICFTSGTTGDPKGAMLTHENVVSNMAAFLKFLEPIFQPTSDDVTISYLPLAHMFERLVQ 316

  Fly   277 VFLGLSHAGCVTFADKDALKGTLIKTFRKA-RPTKMFGVPRVFEKLQERLVAAEAKARPYSRLLL 340
            ..| .|..|.:.|...|.   .|:....|| :||....|||:..::.:: |..|||. |..:.||
Mouse   317 GIL-FSCGGKIGFFQGDI---RLLPDDMKALKPTVFPTVPRLLNRVYDK-VQNEAKT-PLKKFLL 375

  Fly   341 ARARAAVAEHQTTLMAG--KSPSIYGNAKYWLACRVVKPIREMIGVDNCRVFFTGGAPTSEELKQ 403
               ..|:......:..|  :..|::...       |...|:..:| ...|:..||.||.|..:..
Mouse   376 ---NLAIISKFNEVKNGIIRRDSLWDKL-------VFSKIQGSLG-GKVRLMITGAAPISTPVLT 429

  Fly   404 FFLGLDIALG----ECYGMSETSG--AITLNVDISNLYSAGQ-----ACEGVTLK----IHEPDC 453
            ||..   |:|    |.||.:|.:|  :||...|    ::||.     ||..|.|:    ::....
Mouse   430 FFRA---AMGCWVFEAYGQTECTGGCSITSPGD----WTAGHVGTPVACNFVKLEDVADMNYFSV 487

  Fly   454 NGQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGRLKELIITAGGEN 518
            |.:|||.::|..||.|||..|:||:|.:.:|||||:||:|...|.|.|.|..|.|.:...|.||.
Mouse   488 NNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKIVDRKKNIFKLAQGEY 552

  Fly   519 IPPVHIEELIKKELPCVSNVLLIGDH-RKYLTVLLSLKTKCDAKTGIPLDALREETIEWLRDLDI 582
            |.|..||.:..:..| |..|.:.|:. |.:|..::
Mouse   553 IAPEKIENVYSRSRP-VLQVFVHGESLRSFLIGVV------------------------------ 586

  Fly   583 HETRLSELLNIPADLQLPNDTAALA--ATLEITAKPKLL-EAIEEGIKRANKY-AISNAQKVQKF 643
                      :|....||:..|.:.  .:.|...|.:.: |||.|.:::..|. .:.:.::|:..
Mouse   587 ----------VPDPDSLPSFAAKIGVKGSFEELCKNQCVKEAILEDLQKIGKEGGLKSFEQVKSI 641

  Fly   644 ALIAHEFSVATGELGPTLKIRRNIVHAKYAKV-IERLYK 681
            .:....|::..|.|.||||.:| :..||:.:. |:.||:
Mouse   642 FVHPEPFTIENGLLTPTLKAKR-VELAKFFQTQIKSLYE 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	169/660 (26%)
Acsl5	NP_082252.1	LC-FACS_euk	101..678	CDD:341250	168/657 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810