Protein Alignment hll and acsbg2

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001119851.1
• Gene: acsbg2 / 335159
• ZFINID: ZDB-GENE-030131-7099
• Length: 752
• Species: Danio rerio
• Alignment Length: 691
• Identity: 268/691 - (38%)
• Similarity: 393/691 - (56%)
• Gaps: 61/691 - (8%)

  Fly     8 TSYRSTSLHDAVKLRLDEPSSFSQTVPPQTIPEFFKESCEKYSDLPALVWETPGSGNDGWTTLTF 72
            |...:|.....||||:.|....::|  |.|:.:.|..:.:::...|||.|:.    .:.|.|:|:
Zfish    91 TELWTTHRDGEVKLRMAESGLGAET--PLTVNQMFTSTVQRFGSYPALGWKE----GEQWKTMTY 149

  Fly    73 GEYQERVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVL 137
            .||.:....||...|.:|:|....||||.||..|||.|:..|:.||....|:|.:||.||..:|.
Zfish   150 SEYYKSCRTAAKSFLKLGLERYHGVGILGFNSTEWFIADIAAILAGGFAVGIYTTNSPEACQYVA 214

  Fly   138 ATGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSELK 202
            ...::::.||::.:|:.|:..|:::||.|||:||..   :...:.:|..::|.:..|
Zfish   215 ENCQANILVVENHKQLQKILQIQDKLPHLKAIIQYK---DELKEKKPNLYTWAEFME-------- 268

  Fly   203 EELLARE----------SRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAH--MQDIQ 255
               |.|:          |..:.|:|..||:||||.|.||.||||||||.:...:.:.|  :.|..
Zfish   269 ---LGRDEPDTQLDDIISSQKPNQCCTLIYTSGTTGQPKGVMLSHDNLTWTAVATSQHVSLNDAD 330

  Fly   256 VGKESFVSYLPLSHVAAQIFDVFLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFEK 320
            ..:|..||||||||:|||:.|::|.:...|...||..|||||:|..|.|:.|||...|||||:||
Zfish   331 KLQEVVVSYLPLSHIAAQMIDIWLPMKAGGVTYFAQPDALKGSLANTLREIRPTAFLGVPRVWEK 395

  Fly   321 LQERLVAAEAKARPYSRLLLARARAAVAEHQTTLMA----GKSPSIYGNAKYWLACRVVKPIREM 381
            :||::.:..||:....|.:.:.|:....:.....|.    .:.|..|..||:    .|.:.:|:.
Zfish   396 MQEKMKSIGAKSSTVRRKVASWAKDVGLQTNLNKMELGSNSRKPLNYRLAKH----LVFRKVRKA 456

  Fly   382 IGVDNCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSETSGAITL-NVDISNLYSAGQACEGVT 445
            :|:|.|...:||.||.:::..:|||.|||.|.|.|||||:||..|: ..:...|.|.|:...|..
Zfish   457 LGLDRCTRCYTGAAPITKDTLEFFLSLDIPLFELYGMSESSGPHTITQANAFRLTSCGKVIPGCK 521

  Fly   446 LKIHEPDCNGQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGRLKEL 510
            .|:..||....|||...||.||||||.:||||||.:..:|||||||||.:|....|.|:||:|||
Zfish   522 TKLSNPDDEKNGEICFWGRHVFMGYLNMPDKTEEALDAEGWLHSGDLGKLDENNFLFITGRIKEL 586

  Fly   511 IITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLDALREETIE 575
            ||||||||||||.||:.:|:.:|.:||.:||||.||:|::||::|.:.:.:||:|.|.|..|.:|
Zfish   587 IITAGGENIPPVPIEDAVKEAIPLISNAMLIGDKRKFLSMLLTVKCQINGETGVPEDELTPEAVE 651

  Fly   576 WLRDLDIHETRLSELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKYAISNAQKV 640
            :.|.|....||::|:..       ..|.|..|             ||::||.|.|:.|.||||::
Zfish   652 FCRKLGSSCTRVTEIAG-------GRDRAVQA-------------AIQDGINRVNEKATSNAQRI 696

  Fly   641 QKFALIAHEFSVATGELGPTLKIRRNIVHAKYAKVIERLYK 681
            ||:.::..:||:..||||||:|::|.:|...|.:.||..||
Zfish   697 QKWTVLDQDFSIPGGELGPTMKLKRPVVMKMYKEQIESFYK 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	251/634 (40%)
acsbg2	NP_001119851.1	FAA1	118..738	CDD:223953	259/662 (39%)
		ACSBG_like	139..736	CDD:213299	251/638 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I4520
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58630
OrthoDB	1	1.010	-	-		D218492at33208
OrthoFinder	1	1.000	-	-		FOG0003543
OrthoInspector	1	1.000	-	-		mtm6618
orthoMCL	1	0.900	-	-		OOG6_101481
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6795
SonicParanoid	1	1.000	-	-		X2420
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.820