Protein Alignment hll and Acsbg2

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_001034203.1
• Gene: Acsbg2 / 328845
• MGIID: 3587728
• Length: 667
• Species: Mus musculus
• Alignment Length: 681
• Identity: 245/681 - (35%)
• Similarity: 388/681 - (56%)
• Gaps: 52/681 - (7%)

  Fly    12 STSLHDAVKLRLDEPSSFSQTVPPQTIPEFFKESCEKYSDLPALVWETPGSGNDGWTTLTFGEYQ 76
            ||.....|.|||.:.....:|  |.||||.|:||.|::|..|||.    ......|.||||.:|.
Mouse    25 STHCDGEVLLRLSKHGPGHET--PMTIPELFQESAERFSAYPALA----SKNGKKWDTLTFSQYY 83

  Fly    77 ERVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVLATGE 141
            |...:||..|:.:|::....||||.||..||.....|.:.||.:..|:|.:|||||..:|:....
Mouse    84 EMCRKAAKSLIKLGLQRFQCVGILGFNSVEWVVTALGTILAGGLCVGIYATNSAEACQYVIQQAN 148

  Fly   142 SSVCVVDDAQQMAKLRAI-KERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQE---QTFSSELK 202
            .|:.:|::.||:.|:..| .:::..:||::|...|   .::.....:||....|   ...:.:|.
Mouse   149 VSILIVENDQQLQKILLIPPDKMETVKAIVQYKLP---LMESMANLYSWNDFMELGNDIPNIQLD 210

  Fly   203 EELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDIQV----GKE-SFV 262
            ..:|::    :||:||::::||||.|.||.|:|||||:   |.:|.|..|::::    ||: :.|
Mouse   211 RVILSQ----KANQCAVILYTSGTTGTPKGVLLSHDNI---TWTAGAMSQEMEINRVSGKQNTIV 268

  Fly   263 SYLPLSHVAAQIFDVFLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFEKLQERLVA 327
            |||||||:|||:.|:::.:.......||..|||:|||:.|.::.:||...||||::||:|:.:..
Mouse   269 SYLPLSHIAAQLTDIWIPIKIGALTFFAQPDALRGTLVYTLQEVKPTLFMGVPRIWEKMQDTIKE 333

  Fly   328 AEAKARPYSRLLLARARAAVAEHQTTLMAGKS--PSIYGNAKYWLACRVVKPIREMIGVDNCRVF 390
            ..|::....:...|.|:....:..|..|.||.  |..|..||    ..|...:|..:|:|||..|
Mouse   334 NVARSSRLRKKAFAWAKMLGLKVNTKRMLGKRDIPMNYRMAK----ALVFAKVRTSLGLDNCHAF 394

  Fly   391 FTGGAPTSEELKQFFLGLDIALGECYGMSETSGAITL-NVDISNLYSAGQACEGVTLKIHEPDCN 454
            |:..:|.|:::.:|||.|||.:||.|||||.||..|: |..:..:.|.|:...|....::..:..
Mouse   395 FSSASPLSQDVSEFFLSLDIPIGEIYGMSECSGPHTVSNKSVYRVLSCGKVLSGCKNMLYNQNKE 459

  Fly   455 GQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGRLKELIITAGGENI 519
            |.||:.|.||.||||||...:.|.|.:.|:|||||||:|.:|....|.|:||:||::|||||||:
Mouse   460 GVGEVCMWGRHVFMGYLNKEEATLEALDENGWLHSGDIGRLDSHDFLYITGRIKEILITAGGENV 524

  Fly   520 PPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLDALREETIEWLRDLDIHE 584
            .|:.||.|:|:::|.:|:.:|:||..|:|.:||:||.:.|.|:|.||:.|..|...:.:.|....
Mouse   525 SPIPIETLVKEKIPIISHAMLVGDKAKFLCMLLTLKCETDRKSGEPLNKLSVEAKSFCQMLGSQA 589

  Fly   585 TRLSELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKYAISNAQKVQKFALIAHE 649
            |.:|::|.                    :....:..||:.||...|:.|:|::.:::|:.::..:
Mouse   590 TTVSDILK--------------------SRDQVVYTAIQYGIDIVNQQAMSDSHRIRKWIILEKD 634

  Fly   650 FSVATGELGPTLKIRRNIVHAKYAKVIERLY 680
            ||:..||||||.|::|:::..||...|:.:|
Mouse   635 FSIQGGELGPTSKLKRSVITQKYKAQIDSMY 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	224/629 (36%)
Acsbg2	NP_001034203.1	ACSBG_like	69..665	CDD:341256	224/629 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	377	1.000	Domainoid score	I857
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	504	1.000	Inparanoid score	I1335
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58630
OrthoDB	1	1.010	-	-		D218492at33208
OrthoFinder	1	1.000	-	-		FOG0003543
OrthoInspector	1	1.000	-	-		mtm8766
orthoMCL	1	0.900	-	-		OOG6_101481
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6795
SonicParanoid	1	1.000	-	-		X2420
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.870