Protein Alignment hll and LOC316124

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_006244385.1
• Gene: LOC316124 / 316124
• RGDID: 1595856
• Length: 705
• Species: Rattus norvegicus
• Alignment Length: 695
• Identity: 216/695 - (31%)
• Similarity: 347/695 - (49%)
• Gaps: 63/695 - (9%)

  Fly     9 SYRSTSLHDAVKLRLDEPSSFSQTVPPQTIPEFFKESCEKYSDLPALVWETPGSG-NDGWTTLTF 72
            :|.::.....|:||:.:  :..:..||.|:|:....:..|||...|:     ||. ...|..||:
  Rat    48 NYWTSKREGQVQLRMGK--NPLENEPPVTVPDLIMSAATKYSHYLAI-----GSKYKKSWQVLTY 105

  Fly    73 GEYQERVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVL 137
            .||.|...:||...|.||:|....|||:..|..||..|..||:.||.:..|:..|||.:|...:.
  Rat   106 IEYYEACRRAAKAFLKVGLERFHGVGIMGINSSEWVIASIGAIMAGGISVGILSSNSPKACQIIA 170

  Fly   138 ATGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQE--QTFSSE 200
            .|.|..:.|||:.:|:.|:..|:..|..|||:||..   |...:.:|..:||:...:  ...|.|
  Rat   171 ETSEMDIFVVDNDRQLQKVNQIQGYLKHLKAIIQYR---EDIQEVQPNLYSWKGFLDLADGISDE 232

  Fly   201 LKEELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDIQV-----GKES 260
            ..::::..:   :.|:|..|::..||.|.|||:||||||:.:.|   ||.:|.:..     |:|.
  Rat   233 KLDQIIDAQ---KPNQCCALVYNQGTTGNPKAIMLSHDNITWTT---AATVQSLGYKCPPHGQEI 291

  Fly   261 FVSYLPLSHVAAQIFDVFLGLSHAGCVTFADKDALK----------GTLIKTFRKARPTKMFGVP 315
            .||||||.....||.||::.:|.||.|.|...::.|          |.|::..|:.:||...|:|
  Rat   292 LVSYLPLCFAGIQILDVWVAISVAGTVYFPSLESGKWSGLPRVSGTGFLMELLREVQPTTFCGIP 356

  Fly   316 RVFEKLQERLVAAEAKARPYSRLLLARA-RAAVAEHQTTLMAG-KSPSIYGNAKYWLACRVV-KP 377
            .|::::.:.|......:..:.|.:...| |..::.::..:|.| ..|..:|.||     |:. ||
  Rat   357 WVWDRMLDSLKTKHLDSTAFRRKIDRWAMRMGLSTNKRQMMGGIHQPLCFGLAK-----RLTFKP 416

  Fly   378 IREMIGVDNCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSETSGAITL-NVDISNLYSAGQAC 441
            .::.:|:::|..|...|.........|||.::|.:.|.||:||.:|..|| ::....:.|:|:|.
  Rat   417 AKKFLGLNHCEQFLNVGMGLPRSTLDFFLSMNIPILELYGLSECTGLHTLSSLQAYRILSSGKAL 481

  Fly   442 EGVTLKIHEPDCNGQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGR 506
            .....|:.:.:.:|.|.:.:.||.||||||.....||..|...||||:.|||::|....|.::|.
  Rat   482 PKTHTKVEKENQDGVGNLCIWGRHVFMGYLRDKHSTERKVDNHGWLHTNDLGFLDFDKYLYVTGN 546

  Fly   507 LKELIITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLDALRE 571
            ..:||....||.:.|:.|||.::..:|.|...:|:|....||..||:||.:.:.:||.....|..
  Rat   547 TNDLIRLNSGEMVNPIPIEERVRTRIPLVRYAMLVGQDAPYLCALLTLKCQINPETGEAQGNLTS 611

  Fly   572 ETIEWLRDLDIHETRLSELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKYAISN 636
            |.|...|.|....|.||::|                    ....|.:.:.|::||:..|..|.|.
  Rat   612 EAIACCRKLRSQSTWLSDVL--------------------YNRDPLVTQFIDQGIQDVNSEAPSV 656

  Fly   637 AQKVQKFALIAHEFSVATGELGPTLKIRRNIVHAKYAKVIERLYK 681
            ..|:.|:.::.::|||..|||||..|:.|:.|...|.:.|::||:
  Rat   657 GAKIIKWVILDNDFSVDGGELGPMSKMNRSTVIKIYKEEIQKLYE 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	201/639 (31%)
LOC316124	XP_006244385.1	FAA1	74..701	CDD:223953	209/665 (31%)
		ACSBG_like	95..700	CDD:213299	200/638 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D218492at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101481
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750