Protein Alignment hll and Acsbg2

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_006244373.1
• Gene: Acsbg2 / 301120
• RGDID: 1588580
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 689
• Identity: 257/689 - (37%)
• Similarity: 398/689 - (57%)
• Gaps: 46/689 - (6%)

  Fly     1 MNDLKPATSYRSTSLHDAVKLRLDEPSSFSQTVPPQTIPEFFKESCEKYSDLPALVWETPGSGND 65
            |:....|....||.....|.|||.:.....:|  |.||||.|:||.|::...|||.    .....
  Rat    45 MDTTSAAPRLWSTHCDGEVLLRLSKHGPGHET--PMTIPELFQESVERFGAYPALA----SKNGK 103

  Fly    66 GWTTLTFGEYQERVEQAALMLLSVGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSA 130
            .|.||||.:|.:...:||..|:.:|::....||||.||..||..|..||:.||.:..|:|.:|||
  Rat   104 KWDTLTFSQYYDVCRKAARSLIKLGLQRFHGVGILGFNSVEWVVAALGAILAGGLCVGIYATNSA 168

  Fly   131 EAVHHVLATGESSVCVVDDAQQMAKLRAI-KERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQE 194
            ||..:|:.....:|.:|::.||:.|:.:| .:::..:||::|...|   .:::....:|||...|
  Rat   169 EACQYVIKQANVNVLIVENDQQLQKILSIPPDKMETVKAIVQYRLP---LMENSTNLYSWQDFME 230

  Fly   195 ---QTFSSELKEELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDIQV 256
               ...:.:|...:|::    :||:||::|:||||.|.||.|||||||:.:...:.|..::.|.|
  Rat   231 LGNAIPNIQLDRVILSQ----KANQCAVIIYTSGTTGSPKGVMLSHDNITWTAGAMAREIELIHV 291

  Fly   257 -GK-ESFVSYLPLSHVAAQIFDVFLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFE 319
             || ::.||||||||:|||:.|:::.:.......||..|||:|||:.|.::.:||...|||||:|
  Rat   292 SGKQDTIVSYLPLSHIAAQLMDIWIPIKVGVLTFFAQPDALRGTLVYTLQEVKPTYFLGVPRVWE 356

  Fly   320 KLQERLVAAEAKARPYSRLLLARARAAVAEHQTTLMAGKS--PSIYGNAKYWLACRVVKPIREMI 382
            |:|:.:....||:....:...|.|:....:..|..|.||.  |..|..||    ..|...:|..:
  Rat   357 KMQDTIKENVAKSSNLRKKAFAWAKMLGLKVNTKKMLGKRDIPMNYRMAK----ALVFTKVRTSL 417

  Fly   383 GVDNCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSETSGAITLNV-DISNLYSAGQACEGVTL 446
            |:|||..||:|.:|.|:::.:|||.|||.:||.|||:|.||..|::. .|..:.|.|:...|...
  Rat   418 GLDNCHTFFSGASPLSQDVSEFFLSLDIPIGEIYGMTECSGPHTVSCKSIYRVLSCGKVLNGCKN 482

  Fly   447 KIHEPDCNGQGEILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGRLKELI 511
            .:::.:.:|.||:.|.||.|||||||..|.|.|.:.|||||||||:|.:|....|.|:||:||::
  Rat   483 MLYKQNKDGVGEVCMWGRHVFMGYLGKEDATLEVLDEDGWLHSGDIGRLDSHDFLYITGRIKEVL 547

  Fly   512 ITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLDALREETIEW 576
            ||||||||.|:.||.|:|:::|.:|:.:|:||..|:|::||:||.:.|..:|.|||.|..|.|.:
  Rat   548 ITAGGENIWPIPIETLVKEKIPIISHAMLVGDKAKFLSMLLTLKCETDQMSGEPLDKLNLEAISF 612

  Fly   577 LRDLDIHETRLSELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKYAISNAQKVQ 641
            .:.|......:|::|.|                    ..|.:..||:.||...|:.|:|::.:::
  Rat   613 CQMLGSQAVTVSDILKI--------------------RDPVVYTAIQYGIDIVNQQAVSDSHRIR 657

  Fly   642 KFALIAHEFSVATGELGPTLKIRRNIVHAKYAKVIERLY 680
            |:.::..:||:..||||||.|::|:::..||...|:.:|
  Rat   658 KWIILEKDFSIQGGELGPTSKLKRDLITQKYKAQIDNMY 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	235/626 (38%)
Acsbg2	XP_006244373.1	FAA1	78..698	CDD:223953	247/654 (38%)
		AFD_class_I	100..696	CDD:302604	235/626 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	382	1.000	Domainoid score	I795
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	509	1.000	Inparanoid score	I1269
OMA	1	1.010	-	-		QHG58630
OrthoDB	1	1.010	-	-		D218492at33208
OrthoFinder	1	1.000	-	-		FOG0003543
OrthoInspector	1	1.000	-	-		mtm9012
orthoMCL	1	0.900	-	-		OOG6_101481
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2420
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.880