Protein Alignment hll and Slc27a5

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_033538.2
• Gene: Slc27a5 / 26459
• MGIID: 1347100
• Length: 689
• Species: Mus musculus
• Alignment Length: 674
• Identity: 140/674 - (20%)
• Similarity: 225/674 - (33%)
• Gaps: 177/674 - (26%)

  Fly    34 PPQTIPEFFKESCEKYSDLPALVWETPGSGNDGWTTLTFGEYQERVEQAALML-------LSVGV 91
            ||:|..:..:.....:.|..|||.    :|::| :::|..:...|..|||.:|       :....
Mouse   111 PPETFVDALERQALAWPDRVALVC----TGSEG-SSITNSQLDARSCQAAWVLKAKLKDAVIQNT 170

  Fly    92 EERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYP-SNSAEAVHHVLATGESSVCVVDDAQQMAK 155
            .:.:::.:|............|..:.|..||.:.| |.....:|.|.::|.|.:.|..|.|:
Mouse   171 RDAAAILVLPSKTISALSVFLGLAKLGCPVAWINPHSRGMPLLHSVRSSGASVLIVDPDLQE--- 232

  Fly   156 LRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSELKEELLARESRIRANECAML 220
              .::|.||:|.|. .:|..:.......||..:.....:...|..:...|.|   .|:....|:.
Mouse   233 --NLEEVLPKLLAE-NIHCFYLGHSSPTPGVEALGASLDAAPSDPVPASLRA---TIKWKSPAIF 291

  Fly   221 IFTSGTVGMPKAVMLSH-----------------DNLVFDTKSAAAHMQDIQVGKESFVSYLPLS 268
            ||||||.|:||..:|||                 |::|:|.                    |||.
Mouse   292 IFTSGTTGLPKPAILSHERVIQVSNVLSFCGCRADDVVYDV--------------------LPLY 336

  Fly   269 HVAAQIFDVFLGLSHAG--CVTFADKDALKGTLIKTFRKAR---PTKMFGVPRVFEKLQERLVAA 328
            |....:.. |||....|  ||           |...|..:|   ..:..||..:....:......
Mouse   337 HTIGLVLG-FLGCLQVGATCV-----------LAPKFSASRFWAECRQHGVTVILYVGEILRYLC 389

  Fly   329 EAKARPYSRLLLARARAAVAEHQTTLMAGKSPSIYGNAKYWLACRVVKPIREMIGVDNCRVF-FT 392
            ....:|..::           |...|..|..          |...|.|..::..|  ..|:: |.
Mouse   390 NVPEQPEDKI-----------HTVRLAMGNG----------LRANVWKNFQQRFG--PIRIWEFY 431

  Fly   393 GGAPTSEELKQFFLGLDIALGECYGMSETSGAITL-------NVDISNLYSAGQACEGVTLKIHE 450
            |....:       :||...:|.|..:..||..:.:       ..||......... :|..:.: |
Mouse   432 GSTEGN-------VGLMNYVGHCGAVGRTSCILRMLTPFELVQFDIETAEPLRDK-QGFCIPV-E 487

  Fly   451 PDCNGQGEILMRGRLVFMGYLGLPDKTEETVK--------EDGWLHSGDLGYIDPKGNLIISGRL 507
            |...|.....:|....|:||.|  .:.|...|        .|.:.::||:..:|.:|......||
Mouse   488 PGKPGLLLTKVRKNQPFLGYRG--SQAESNRKLVANVRRVGDLYFNTGDVLTLDQEGFFYFQDRL 550

  Fly   508 KELIITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPL------ 566
            .: .....|||:....:|        ||.:.|   |..:.:.|.......|:.|.|:..
Mouse   551 GD-TFRWKGENVSTGEVE--------CVLSSL---DFLEEVNVYGVPVPGCEGKVGMAAVKLAPG 603

  Fly   567 -----DALREETIEWLRDLDI-HETRLSELLNIPADLQLPNDTAALAATLEITAKPKLL------ 619
                 ..|.:....||..... |..|:.:                   :||||...||:
Mouse   604 KTFDGQKLYQHVRSWLPAYATPHFIRIQD-------------------SLEITNTYKLVKSRLVR 649

  Fly   620 EAIEEGIKRANKYAISNAQKVQKF 643
            |..:.||.....|.:.|  |.|.|
Mouse   650 EGFDVGIIADPLYILDN--KAQTF 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	133/646 (21%)
Slc27a5	NP_033538.2	PRK08279	100..685	CDD:236217	140/674 (21%)
		AFD_class_I	139..679	CDD:302604	132/642 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839230
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930