Protein Alignment hll and acs-10

DIOPT Version :9

• Sequence 1: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_506502.1
• Gene: acs-10 / 179913
• WormBaseID: WBGene00007082
• Length: 566
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 150/672 - (22%)
• Similarity: 260/672 - (38%)
• Gaps: 175/672 - (26%)

  Fly    30 SQTVP----PQTIPEFFKESCEKY--SDLPALVWETPGSGNDGWTTL---TFGEYQERVEQAALM 85
            |:.||    .|.:.|...:||..:  ::..|:|:      .|..||.   .:.:.:..|...|..
 Worm     5 SKAVPLKLSTQPVHERILDSCRIHAAANKDAIVF------IDAETTTKKKLYRDVEPTVNSLATA 63

  Fly    86 LLSVGVEERSSVGILAF-NCPEWFFAEFGALRAGAVVAGVYPSNSAEAV----HHVLATGESSVC 145
            |:.:|.:. ..|...|| ||||:..|....::.|..:      ::|.|:    ...|...:|:..
 Worm    64 LVKLGFKP-GDVAAQAFPNCPEFLIAMLAVMKCGGAM------SNASAIFTDYELQLQFKDSNTS 121

  Fly   146 VV-DDAQQMAKLRAIKERLPRLKAVIQLHG-PFEA-FVDHEPGYFSWQKLQEQTFSSELKEELLA 207
            :| .|..::|::|....:.|.::.:|.|.. |..| |.::...:....:..:|..:..:..:.:
 Worm   122 IVFTDEDRLARVRRSVAKCPGVRKIICLRTFPLRAEFPENVLDFVELTQTPDQPINVVVSPDAI- 185

  Fly   208 RESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDIQVGKESFVSYLPL---SH 269
                      |:|.::|||.|.||...|:|.|:......|.:|: :.:|.:..|....|.   .|
 Worm   186 ----------ALLPYSSGTTGRPKGCQLTHKNISAMLDIAQSHL-ETEVAQAMFGKEKPTWNKEH 239

  Fly   270 VAAQIFDVFLGLSHA-GCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFEKLQERLVAAEAKAR 333
            |.     :.|...|| |..|..:...|..|.:                ||:|....::
 Worm   240 VL-----LLLPWYHAYGLNTMLETILLGATGL----------------VFKKFDTIVM------- 276

  Fly   334 PYSRLLLARARAAVAEHQTTLMAGKSP--SIYGNAKYWLACRVVKPIREMIGVDNCRVFFTGGAP 396
             .:|:...:.:.|.......:...|.|  .|:..|.|                  .:|..:.||.
 Worm   277 -LNRIKFYKVKLAWLVPPMLIFLAKDPMVPIFNVAPY------------------LKVIMSAGAT 322

  Fly   397 TSEEL-----KQFFLGLDIALGECYGMSETSGAITLNVDISNLYSAGQACE-----GVTLKIHEP 451
            ..::|     |:|   .:..|.:.|||:|.....||.:     :..|...|     |.|.::...
 Worm   323 AGKQLCEEVQKRF---PNAWLCQAYGMTEMVQFTTLPI-----FEHGNCFETVGSLGPTYEMKIL 379

  Fly   452 DCNGQ--------GEILMRGRLVFMGYLGLPDKTEET--VKEDGWLHSGDLGYIDPKGNLIISGR 506
            |..|:        |::..||..:..|||    |.||:  :.:||:|.:||||.:|.||.:.::||
 Worm   380 DKEGKEVDKTDTVGQLCFRGPTIMKGYL----KKEESDIIDKDGFLKTGDLGSVDQKGRVHVTGR 440

  Fly   507 LKELIITAGGENIPPVHIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIPLDALRE 571
            :||| |...|..:|||.||:::                      ||..|.|..|..|||.:...|
 Worm   441 IKEL-IKVNGMQVPPVEIEDVL----------------------LLHPKVKDCAVIGIPDEQKGE 482

  Fly   572 ETIEWL--RDLDIHETRLSELLN--------------IPADLQLPNDTAALAATLEITAKPKLLE 620
            ....::  :|..:.|..||:.::              |.|..:||:.        :|..| ||.|
 Worm   483 SPRAYIVKKDHTLTEAELSDFVHKMLSSYKWIDTYEFIDAIPKLPSG--------KIQRK-KLKE 538

  Fly   621 AIEEGIKRANKYAISNAQKVQK 642
            ....|....|..|..:::::.:
 Worm   539 MAAGGGSTENSEASQSSKEISE 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	141/634 (22%)
acs-10	NP_506502.1	CaiC	17..544	CDD:223395	143/642 (22%)
		Firefly_Luc_like	37..532	CDD:213279	134/609 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160497
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930